RA CAPITAL MANAGEMENT, L.P. / RA Capital Healthcare Fund LP / RA Capital Nexus Fund III, L.P. / Peter Kolchinsky / Rajeev M. Shah

Insider

Director, 10% Owner

Trades at: TYRA· BCAX· EVMN

30D 90D 1Y

Net shares · 365d

+27.7M

27.7M buy · 0 sell

Net value · 365d

$531.6M

$531.6M in · $0 out

Sentiment · 365d

Net buying

100% buying · 0% selling

Open-market trades · 365d

27.7M buy · 0 sell

Net buy / sell volume (all companies)

Tap or hover the chart for daily net volume. Green = net buying, red = net selling.

All transactions

Show open-market only

TYRA Exercise·C
Jun 11, 26

Director, 10% Owner

—

1.7M sh

Own New
TYRA Exercise·C
Jun 11, 26

Director, 10% Owner

—

9.4M sh

Own New
TYRA Exercise·C
Jun 11, 26

Director, 10% Owner

—

160.6K sh

Own New
TYRA Exercise·C
Jun 11, 26

Director, 10% Owner

—

642.2K sh

Own New
TYRA Buy·P
Jun 11, 26

Director, 10% Owner

$29.2M

1.5M sh · $20.00

Own +123%
TYRA Buy·P
Jun 11, 26

Director, 10% Owner

$394.6M

19.7M sh · $20.00

Own +301%
TYRA Exercise·C
Jun 11, 26

Director, 10% Owner

—

1.2M sh

Own New
TYRA Exercise·C
Jun 11, 26

Director, 10% Owner

—

6.6M sh

Own New
BCAX Grant·A
Jun 9, 26

Director, 10% Owner

$0

19.5K sh

Own New
TYRA Grant·A
Jun 9, 26

Director

$0

20.2K sh

Own New
TYRA Buy·P
Mar 30, 26

Director

$1.4M

58.3K sh · $24.16

Own +1%
TYRA Buy·P
Mar 27, 26

Director

$7.4M

310.7K sh · $23.67

Own +6%
BCAX Buy·P
Feb 26, 26

Director, 10% Owner

$35.2M

2.2M sh · $16.00

Own New
BCAX Buy·P
Feb 26, 26

Director, 10% Owner

$4.8M

300.0K sh · $16.00

Own +7%
TYRA Grant·A
Feb 19, 26

Director

$0

8.3K sh

Own New
TYRA Grant·A
Feb 19, 26

Director

$0

6.2K sh

Own New
EVMN Grant·A
Feb 17, 26

Director

$1000.0K

35.9K sh · $27.88

Own +1%
TYRA Exercise·C
Feb 9, 26

Director, 10% Owner

—

272.1K sh

Own New
TYRA Exercise·C
Feb 9, 26

Director, 10% Owner

—

222.6K sh

Own New
TYRA Exercise·C
Feb 9, 26

Director, 10% Owner

—

767.3K sh

Own New
TYRA Exercise·C
Feb 9, 26

Director, 10% Owner

—

1.2M sh

Own New
TYRA Buy·P
Feb 9, 26

Director, 10% Owner

$4.0M

248.0K sh · $16.00

Own +14%
TYRA Buy·P
Feb 9, 26

Director, 10% Owner

$55.1M

3.4M sh · $16.00

Own +136%
TYRA Exercise·C
Feb 9, 26

Director, 10% Owner

—

1.8M sh

Own New
TYRA Exercise·C
Feb 9, 26

Director, 10% Owner

—

2.5M sh

Own New
TYRA Grant·A
Feb 5, 26

Director, 10% Owner

$0

27.4K sh

Own New

Date▾	Ticker	Role	Type	Shares	Own Δ	Price	Value
Jun 11, 2026	TYRA	Director, 10% Owner	Exercise C	1.7M	New	—	—
Jun 11, 2026	TYRA	Director, 10% Owner	Exercise C	9.4M	New	—	—
Jun 11, 2026	TYRA	Director, 10% Owner	Exercise C	160.6K	New	—	—
Jun 11, 2026	TYRA	Director, 10% Owner	Exercise C	642.2K	New	—	—
Jun 11, 2026	TYRA	Director, 10% Owner	Buy P	1.5M	+123%	$20.00	$29.2M
Jun 11, 2026	TYRA	Director, 10% Owner	Buy P	19.7M	+301%	$20.00	$394.6M
Jun 11, 2026	TYRA	Director, 10% Owner	Exercise C	1.2M	New	—	—
Jun 11, 2026	TYRA	Director, 10% Owner	Exercise C	6.6M	New	—	—
Jun 9, 2026	BCAX	Director, 10% Owner	Grant A	19.5K	New	—	$0
Jun 9, 2026	TYRA	Director	Grant A	20.2K	New	—	$0
Mar 30, 2026	TYRA	Director	Buy P	58.3K	+1%	$24.16	$1.4M
Mar 27, 2026	TYRA	Director	Buy P	310.7K	+6%	$23.67	$7.4M
Feb 26, 2026	BCAX	Director, 10% Owner	Buy P	2.2M	New	$16.00	$35.2M
Feb 26, 2026	BCAX	Director, 10% Owner	Buy P	300.0K	+7%	$16.00	$4.8M
Feb 19, 2026	TYRA	Director	Grant A	8.3K	New	—	$0
Feb 19, 2026	TYRA	Director	Grant A	6.2K	New	—	$0
Feb 17, 2026	EVMN	Director	Grant A	35.9K	+1%	$27.88	$1000.0K
Feb 9, 2026	TYRA	Director, 10% Owner	Exercise C	272.1K	New	—	—
Feb 9, 2026	TYRA	Director, 10% Owner	Exercise C	222.6K	New	—	—
Feb 9, 2026	TYRA	Director, 10% Owner	Exercise C	767.3K	New	—	—
Feb 9, 2026	TYRA	Director, 10% Owner	Exercise C	1.2M	New	—	—
Feb 9, 2026	TYRA	Director, 10% Owner	Buy P	248.0K	+14%	$16.00	$4.0M
Feb 9, 2026	TYRA	Director, 10% Owner	Buy P	3.4M	+136%	$16.00	$55.1M
Feb 9, 2026	TYRA	Director, 10% Owner	Exercise C	1.8M	New	—	—
Feb 9, 2026	TYRA	Director, 10% Owner	Exercise C	2.5M	New	—	—
Feb 5, 2026	TYRA	Director, 10% Owner	Grant A	27.4K	New	—	$0

About RA CAPITAL MANAGEMENT, L.P. / RA Capital Healthcare Fund LP / RA Capital Nexus Fund III, L.P. / Peter Kolchinsky / Rajeev M. Shah

This profile aggregates every SEC Form 4 insider transaction reported by RA CAPITAL MANAGEMENT, L.P. / RA Capital Healthcare Fund LP / RA Capital Nexus Fund III, L.P. / Peter Kolchinsky / Rajeev M. Shah across all companies they trade. Open-market purchases (code P) and sales (code S) are the highest-signal, discretionary trades; grants (A), option exercises (M) and gifts (G) reflect compensation rather than conviction and carry no market price. Figures cover the selected period and update as new filings are ingested.