ORBIMED ADVISORS LLC

Insider

Director, 10% Owner

Trades at: ELVN· STTK· QTTB· SION· PRLD· TRAW· IMA· ACET +8 more

30D 90D 1Y

Net shares · 90d

+9.0M

10.2M buy · 1.2M sell

Net value · 90d

-$23.6M

$28.5M in · $52.1M out

Sentiment · 90d

Net buying

35% buying · 65% selling

Open-market trades · 90d

10.2M buy · 1.2M sell

Net buy / sell volume (all companies)

Tap or hover the chart for daily net volume. Green = net buying, red = net selling.

All transactions · open-market

Include grants & non-market

ELVN Sell·S
Jun 15, 26

10% Owner

$12.3M

272.3K sh · $45.02

Own -4%
ELVN Sell·S
Jun 15, 26

10% Owner

$409.1K

9.1K sh · $45.02

Own -4%
STTK Buy·P
Jun 11, 26

Director

—

208.3K sh

Own +4%
STTK Buy·P
Jun 11, 26

Director

—

1.0M sh

Own +4%
QTTB Buy·P
May 28, 26

Director, 10% Owner

$5.0M

625.0K sh · $8.00

Own New
QTTB Buy·P
May 28, 26

Director, 10% Owner

$10.0M

1.2M sh · $8.00

Own +55%
SION Sell·S
May 27, 26

Director · 10b5-1

$4.5K

101 sh · $44.49

Own -0%
SION Sell·S
May 11, 26

Director · 10b5-1

$8.5M

184.6K sh · $46.22

Own -6%
SION Sell·S
May 8, 26

Director · 10b5-1

$2.7M

59.8K sh · $44.58

Own -2%
SION Sell·S
May 7, 26

Director · 10b5-1

$2.2M

48.5K sh · $44.61

Own -2%
PRLD Buy·P
Apr 21, 26

Director, 10% Owner

$5.0M

1.1M sh · $4.44

Own New
PRLD Buy·P
Apr 21, 26

Director, 10% Owner

$7.5M

1.7M sh · $4.44

Own +17%
SION Sell·S
Apr 18, 26

Director · 10b5-1

$131.2K

2.9K sh · $44.52

Own -0%
SION Sell·S
Apr 17, 26

Director · 10b5-1

$2.3M

52.4K sh · $44.68

Own -2%
SION Sell·S
Apr 16, 26

Director · 10b5-1

$10.3M

226.9K sh · $45.34

Own -7%
TRAW Buy·P
Apr 16, 26

10% Owner

—

1.8M sh

Own New
TRAW Buy·P
Apr 16, 26

10% Owner

—

597.7K sh

Own New
TRAW Buy·P
Apr 16, 26

10% Owner

—

597.7K sh

Own New
TRAW Buy·P
Apr 16, 26

10% Owner

$998.2K

597.7K sh · $1.67

Own +99%
SION Sell·S
Apr 15, 26

Director · 10b5-1

$10.5M

235.9K sh · $44.64

Own -7%
SION Sell·S
Apr 14, 26

Director · 10b5-1

$2.1M

47.8K sh · $44.51

Own -1%
IMA Buy·P
Apr 14, 26

Director

—

384.7K sh

Own New
IMA Buy·P
Apr 14, 26

Director

—

336.6K sh

Own New
ACET Sell·S
Apr 8, 26

10% Owner

$263.5K

40.4K sh · $6.52

Own -100%
ACET Sell·S
Apr 8, 26

10% Owner

$204.6K

32.5K sh · $6.29

Own -100%
ACET Sell·S
Apr 7, 26

10% Owner

$15.3K

2.4K sh · $6.38

Own -7%
ACET Sell·S
Apr 7, 26

10% Owner

$191.5K

29.3K sh · $6.53

Own -46%

Date▾	Ticker	Role	Type	Shares	Own Δ	Price	Value
Jun 15, 2026	ELVN	10% Owner	Sell S	272.3K	-4%	$45.02	$12.3M
Jun 15, 2026	ELVN	10% Owner	Sell S	9.1K	-4%	$45.02	$409.1K
Jun 11, 2026	STTK	Director	Buy P	208.3K	+4%	—	—
Jun 11, 2026	STTK	Director	Buy P	1.0M	+4%	—	—
May 28, 2026	QTTB	Director, 10% Owner	Buy P	625.0K	New	$8.00	$5.0M
May 28, 2026	QTTB	Director, 10% Owner	Buy P	1.2M	+55%	$8.00	$10.0M
May 27, 2026	SION	Director	Sell S	101	-0%	$44.49	$4.5K
May 11, 2026	SION	Director	Sell S	184.6K	-6%	$46.22	$8.5M
May 8, 2026	SION	Director	Sell S	59.8K	-2%	$44.58	$2.7M
May 7, 2026	SION	Director	Sell S	48.5K	-2%	$44.61	$2.2M
Apr 21, 2026	PRLD	Director, 10% Owner	Buy P	1.1M	New	$4.44	$5.0M
Apr 21, 2026	PRLD	Director, 10% Owner	Buy P	1.7M	+17%	$4.44	$7.5M
Apr 18, 2026	SION	Director	Sell S	2.9K	-0%	$44.52	$131.2K
Apr 17, 2026	SION	Director	Sell S	52.4K	-2%	$44.68	$2.3M
Apr 16, 2026	SION	Director	Sell S	226.9K	-7%	$45.34	$10.3M
Apr 16, 2026	TRAW	10% Owner	Buy P	1.8M	New	—	—
Apr 16, 2026	TRAW	10% Owner	Buy P	597.7K	New	—	—
Apr 16, 2026	TRAW	10% Owner	Buy P	597.7K	New	—	—
Apr 16, 2026	TRAW	10% Owner	Buy P	597.7K	+99%	$1.67	$998.2K
Apr 15, 2026	SION	Director	Sell S	235.9K	-7%	$44.64	$10.5M
Apr 14, 2026	SION	Director	Sell S	47.8K	-1%	$44.51	$2.1M
Apr 14, 2026	IMA	Director	Buy P	384.7K	New	—	—
Apr 14, 2026	IMA	Director	Buy P	336.6K	New	—	—
Apr 8, 2026	ACET	10% Owner	Sell S	40.4K	-100%	$6.52	$263.5K
Apr 8, 2026	ACET	10% Owner	Sell S	32.5K	-100%	$6.29	$204.6K
Apr 7, 2026	ACET	10% Owner	Sell S	2.4K	-7%	$6.38	$15.3K
Apr 7, 2026	ACET	10% Owner	Sell S	29.3K	-46%	$6.53	$191.5K

About ORBIMED ADVISORS LLC

This profile aggregates every SEC Form 4 insider transaction reported by ORBIMED ADVISORS LLC across all companies they trade. Open-market purchases (code P) and sales (code S) are the highest-signal, discretionary trades; grants (A), option exercises (M) and gifts (G) reflect compensation rather than conviction and carry no market price. Figures cover the selected period and update as new filings are ingested.