CRSP

insider transactions

CRISPR Therapeutics AG — buys & sells by directors, officers and 10% owners (SEC Form 4).

30D 90D 1Y

Cluster buy signal: 2 different insiders made open-market purchases in the last 365 days, totalling $52.6M.

Net shares · 365d

+706.7K

1.0M buy · 303.2K sell

Net value · 365d

$35.0M

$52.6M in · $17.6M out

Sentiment · 365d

Net buying

75% buying · 25% selling

Open-market trades · 365d

1.0M buy · 303.2K sell

Net buy / sell volume

Tap or hover the chart for daily net volume. Green = net buying, red = net selling.

All transactions

Grant·A
Jun 5, 26

George Simeon

Director

$0

13.0K sh

Own New
Grant·A
Jun 5, 26

Fardis Maria

Director

$0

13.0K sh

Own New
Grant·A
Jun 5, 26

Fleming Harold Edward

Director

$0

13.0K sh

Own New
Grant·A
Jun 5, 26

Greene John

Director

$0

13.0K sh

Own New
Grant·A
Jun 5, 26

High Katherine A

Director

$0

13.0K sh

Own New
Grant·A
Jun 5, 26

Mahatme Sandesh

Director

$0

13.0K sh

Own New
Grant·A
Jun 5, 26

Morrison Briggs

Director

$0

13.0K sh

Own New
Grant·A
Jun 5, 26

Rommel Christian

Director

$0

13.0K sh

Own New
Grant·A
Jun 5, 26

Treco Douglas A

Director

$0

13.0K sh

Own New
Grant·A
Jun 5, 26

Behbahani Ali

Director

$0

13.0K sh

Own New
Sell·S
May 29, 26

Patel Naimish

Chief Medical Officer

$210.6K

3.8K sh · $55.62

Own -16%
Grant·A
May 29, 26

KASINGER JAMES R.

General Counsel and Secretary

$0

17.0K sh

Own New
Grant·A
May 29, 26

Patel Naimish

Chief Medical Officer

$0

22.0K sh

Own New
Grant·A
May 29, 26

Prasad Raju KEY

Chief Financial Officer

$0

19.5K sh

Own New
Exercise·M
May 28, 26

Patel Naimish

Chief Medical Officer

—

10.0K sh

Own +100%
Exercise·M
May 28, 26

Patel Naimish

Chief Medical Officer

—

10.0K sh

Own +76%
Sell·S
Mar 23, 26

Prasad Raju KEY

Chief Financial Officer

$173.5K

3.7K sh · $46.78

Own -19%
Sell·S
Mar 23, 26

KASINGER JAMES R.

General Counsel and Secretary

$148.9K

3.2K sh · $46.78

Own -3%
Sell·S
Mar 23, 26

Kulkarni Samarth KEY

Chief Executive Officer

$468.7K

10.0K sh · $46.78

Own -4%
Grant·A
Mar 20, 26

Prasad Raju KEY

Chief Financial Officer

$0

27.5K sh

Own New
Grant·A
Mar 20, 26

Prasad Raju KEY

Chief Financial Officer

$0

38.5K sh

Own New
Exercise·M
Mar 20, 26

Prasad Raju KEY

Chief Financial Officer

—

6.2K sh

Own +100%
Exercise·M
Mar 20, 26

Prasad Raju KEY

Chief Financial Officer

—

6.2K sh

Own +48%
Grant·A
Mar 20, 26

Patel Naimish

Chief Medical Officer

$0

38.5K sh

Own New
Grant·A
Mar 20, 26

Patel Naimish

Chief Medical Officer

$0

30.0K sh

Own New
Grant·A
Mar 20, 26

KASINGER JAMES R.

General Counsel and Secretary

$0

25.0K sh

Own New
Exercise·M
Mar 20, 26

KASINGER JAMES R.

General Counsel and Secretary

—

6.2K sh

Own +109%
Grant·A
Mar 20, 26

KASINGER JAMES R.

General Counsel and Secretary

$0

38.5K sh

Own New
Exercise·M
Mar 20, 26

KASINGER JAMES R.

General Counsel and Secretary

—

6.2K sh

Own +7%
Grant·A
Mar 20, 26

Kulkarni Samarth KEY

Chief Executive Officer

$0

114.2K sh

Own New
Grant·A
Mar 20, 26

Kulkarni Samarth KEY

Chief Executive Officer

$0

81.9K sh

Own New
Exercise·M
Mar 20, 26

Kulkarni Samarth KEY

Chief Executive Officer

—

19.7K sh

Own +100%
Exercise·M
Mar 20, 26

Kulkarni Samarth KEY

Chief Executive Officer

—

19.7K sh

Own +8%
Sell·S
Mar 16, 26

Prasad Raju KEY

Chief Financial Officer

$194.1K

4.0K sh · $48.26

Own -23%
Other·G
Mar 16, 26

Prasad Raju KEY

Chief Financial Officer

$0

750 sh

Own -5%
Sell·S
Mar 16, 26

Prasad Raju KEY

Chief Financial Officer

$282.2K

5.8K sh · $48.26

Own -25%
Sell·S
Mar 16, 26

Patel Naimish

Chief Medical Officer

$152.0K

3.1K sh · $48.26

Own -19%
Sell·S
Mar 16, 26

Kulkarni Samarth KEY

Chief Executive Officer

$499.4K

10.3K sh · $48.26

Own -4%
Sell·S
Mar 16, 26

KASINGER JAMES R.

General Counsel and Secretary

$166.5K

3.5K sh · $48.26

Own -4%
Exercise·M
Mar 14, 26

Prasad Raju KEY

Chief Financial Officer

—

10.0K sh

Own New
Exercise·M
Mar 14, 26

Prasad Raju KEY

Chief Financial Officer

—

6.9K sh

Own +50%
Exercise·M
Mar 14, 26

Prasad Raju KEY

Chief Financial Officer

—

10.0K sh

Own +148%
Exercise·M
Mar 14, 26

Prasad Raju KEY

Chief Financial Officer

—

6.9K sh

Own +41%
Exercise·M
Mar 14, 26

Patel Naimish

Chief Medical Officer

—

8.1K sh

Own +50%
Exercise·M
Mar 14, 26

Patel Naimish

Chief Medical Officer

—

8.1K sh

Own +99%
Exercise·M
Mar 14, 26

Kulkarni Samarth KEY

Chief Executive Officer

—

20.6K sh

Own +50%
Exercise·M
Mar 14, 26

Kulkarni Samarth KEY

Chief Executive Officer

—

20.6K sh

Own +9%
Exercise·M
Mar 14, 26

KASINGER JAMES R.

General Counsel and Secretary

—

6.9K sh

Own +50%
Exercise·M
Mar 14, 26

KASINGER JAMES R.

General Counsel and Secretary

—

6.9K sh

Own +8%
Sell·S
Mar 11, 26

Kulkarni Samarth KEY

Chief Executive Officer

$517.3K

9.8K sh · $52.80

Own -4%
Sell·S
Mar 11, 26

KASINGER JAMES R.

General Counsel and Secretary

$147.8K

2.8K sh · $52.80

Own -3%
Exercise·M
Mar 10, 26

Kulkarni Samarth KEY

Chief Executive Officer

—

19.2K sh

Own New
Exercise·M
Mar 10, 26

Kulkarni Samarth KEY

Chief Executive Officer

—

19.2K sh

Own +9%
Exercise·M
Mar 10, 26

KASINGER JAMES R.

General Counsel and Secretary

—

5.5K sh

Own New
Exercise·M
Mar 10, 26

KASINGER JAMES R.

General Counsel and Secretary

—

5.5K sh

Own +6%
Sell·S
Feb 19, 26

KASINGER JAMES R.

General Counsel and Secretary

$111.0K

2.1K sh · $52.58

Own -2%
Sell·S
Feb 19, 26

Kulkarni Samarth KEY

Chief Executive Officer

$366.3K

7.0K sh · $52.58

Own -3%
Exercise·M
Feb 18, 26

KASINGER JAMES R.

General Counsel and Secretary

—

3.8K sh

Own New
Exercise·M
Feb 18, 26

KASINGER JAMES R.

General Counsel and Secretary

—

3.8K sh

Own +5%
Exercise·M
Feb 18, 26

Kulkarni Samarth KEY

Chief Executive Officer

—

13.2K sh

Own New
Exercise·M
Feb 18, 26

Kulkarni Samarth KEY

Chief Executive Officer

—

13.2K sh

Own +6%
Sell·S
Jan 22, 26

Kulkarni Samarth KEY

Chief Executive Officer · 10b5-1

$3.6M

60.0K sh · $60.23

Own -31%
Exercise·M
Jan 22, 26

Prasad Raju KEY

Chief Financial Officer · 10b5-1

$0

35.0K sh

Own +522%
Sell·S
Jan 22, 26

Prasad Raju KEY

Chief Financial Officer · 10b5-1

$2.1M

35.0K sh · $60.19

Own -84%
Exercise·M
Jan 22, 26

Prasad Raju KEY

Chief Financial Officer · 10b5-1

$1.6M

35.0K sh · $45.15

Own +517%
Sell·S
Jan 20, 26

Kulkarni Samarth KEY

Chief Executive Officer · 10b5-1

$446.3K

8.6K sh · $52.10

Own -4%
Sell·S
Jan 20, 26

Kulkarni Samarth KEY

Chief Executive Officer · 10b5-1

$1.1M

21.4K sh · $51.61

Own -10%
Exercise·M
Jan 6, 26

Prasad Raju KEY

Chief Financial Officer · 10b5-1

$0

6.3K sh

Own +549%
Exercise·M
Jan 6, 26

Prasad Raju KEY

Chief Financial Officer · 10b5-1

$0

23.4K sh

Own +44%
Sell·S
Jan 6, 26

Prasad Raju KEY

Chief Financial Officer · 10b5-1

$1.1M

18.9K sh · $60.18

Own -52%
Sell·S
Jan 6, 26

Prasad Raju KEY

Chief Financial Officer · 10b5-1

$300.2K

5.0K sh · $60.00

Own -29%
Sell·S
Jan 6, 26

Prasad Raju KEY

Chief Financial Officer · 10b5-1

$347.0K

5.8K sh · $60.21

Own -46%
Exercise·M
Jan 6, 26

Prasad Raju KEY

Chief Financial Officer · 10b5-1

$280.9K

6.3K sh · $44.31

Own +21%
Exercise·M
Jan 6, 26

Prasad Raju KEY

Chief Financial Officer · 10b5-1

$1.1M

23.4K sh · $45.15

Own +345%
Sell·S
Dec 22, 25

Prasad Raju KEY

Chief Financial Officer · 10b5-1

$308.2K

5.5K sh · $56.33

Own -41%
Sell·S
Dec 22, 25

Prasad Raju KEY

Chief Financial Officer · 10b5-1

$56.9K

1.0K sh · $56.89

Own -13%
Sell·S
Dec 22, 25

Prasad Raju KEY

Chief Financial Officer · 10b5-1

$194.4K

3.5K sh · $55.10

Own -21%
Other·G
Dec 18, 25

Kulkarni Samarth KEY

Chief Executive Officer

$0

30.0K sh

Own -12%
Sell·S
Oct 17, 25

Kulkarni Samarth KEY

Chief Executive Officer

$3.5M

50.9K sh · $67.91

Own -17%
Exercise·M
Oct 16, 25

Kulkarni Samarth KEY

Chief Executive Officer

—

100.0K sh

Own +50%
Exercise·M
Oct 16, 25

Kulkarni Samarth KEY

Chief Executive Officer

—

100.0K sh

Own +49%
Sell·S
Oct 14, 25

KASINGER JAMES R.

General Counsel and Secretary

$71.7K

1.1K sh · $66.60

Own -1%
Sell·S
Oct 14, 25

Kulkarni Samarth KEY

Chief Executive Officer

$282.5K

4.2K sh · $66.60

Own -2%
Exercise·M
Oct 13, 25

KASINGER JAMES R.

General Counsel and Secretary

—

2.1K sh

Own New
Exercise·M
Oct 13, 25

KASINGER JAMES R.

General Counsel and Secretary

—

2.1K sh

Own +3%
Exercise·M
Oct 13, 25

Kulkarni Samarth KEY

Chief Executive Officer

—

8.3K sh

Own New
Exercise·M
Oct 13, 25

Kulkarni Samarth KEY

Chief Executive Officer

—

8.3K sh

Own +4%
Grant·A
Oct 3, 25

Kulkarni Samarth KEY

Chief Executive Officer

$0

49.5K sh

Own New
Grant·A
Oct 3, 25

Prasad Raju KEY

Chief Financial Officer

$0

16.5K sh

Own New
Grant·A
Oct 3, 25

Patel Naimish

Chief Medical Officer

$0

16.5K sh

Own New
Grant·A
Oct 3, 25

KASINGER JAMES R.

General Counsel and Secretary

$0

16.5K sh

Own New
Other·G
Sep 17, 25

Kulkarni Samarth KEY

Chief Executive Officer

$0

6.0K sh

Own -3%
Sell·S
Aug 18, 25

Kulkarni Samarth KEY

Chief Executive Officer

$760.7K

13.1K sh · $58.15

Own -6%
Exercise·M
Aug 16, 25

Kulkarni Samarth KEY

Chief Executive Officer

—

25.0K sh

Own New
Exercise·M
Aug 16, 25

Kulkarni Samarth KEY

Chief Executive Officer

—

25.0K sh

Own +13%
Buy·P
Aug 6, 25

Treco Douglas A

Director

$1.1M

20.0K sh · $57.03

Own +1000%
Buy·P
Jul 16, 25

George Simeon

Director

$338.7K

6.5K sh · $52.03

Own +10%
Buy·P
Jul 16, 25

George Simeon

Director

$50.0M

961.0K sh · $52.03

Own +125%
Buy·P
Jul 16, 25

George Simeon

Director

$1.2M

22.3K sh · $52.03

Own +10%

Date▾	Insider	Role	Type	Shares	Own Δ	Price	Value
Jun 5, 2026	George Simeon	Director	Grant A	13.0K	New	—	$0
Jun 5, 2026	Fardis Maria	Director	Grant A	13.0K	New	—	$0
Jun 5, 2026	Fleming Harold Edward	Director	Grant A	13.0K	New	—	$0
Jun 5, 2026	Greene John	Director	Grant A	13.0K	New	—	$0
Jun 5, 2026	High Katherine A	Director	Grant A	13.0K	New	—	$0
Jun 5, 2026	Mahatme Sandesh	Director	Grant A	13.0K	New	—	$0
Jun 5, 2026	Morrison Briggs	Director	Grant A	13.0K	New	—	$0
Jun 5, 2026	Rommel Christian	Director	Grant A	13.0K	New	—	$0
Jun 5, 2026	Treco Douglas A	Director	Grant A	13.0K	New	—	$0
Jun 5, 2026	Behbahani Ali	Director	Grant A	13.0K	New	—	$0
May 29, 2026	Patel Naimish	Chief Medical Officer	Sell S	3.8K	-16%	$55.62	$210.6K
May 29, 2026	KASINGER JAMES R.	General Counsel and Secretary	Grant A	17.0K	New	—	$0
May 29, 2026	Patel Naimish	Chief Medical Officer	Grant A	22.0K	New	—	$0
May 29, 2026	Prasad Raju KEY	Chief Financial Officer	Grant A	19.5K	New	—	$0
May 28, 2026	Patel Naimish	Chief Medical Officer	Exercise M	10.0K	+100%	—	—
May 28, 2026	Patel Naimish	Chief Medical Officer	Exercise M	10.0K	+76%	—	—
Mar 23, 2026	Prasad Raju KEY	Chief Financial Officer	Sell S	3.7K	-19%	$46.78	$173.5K
Mar 23, 2026	KASINGER JAMES R.	General Counsel and Secretary	Sell S	3.2K	-3%	$46.78	$148.9K
Mar 23, 2026	Kulkarni Samarth KEY	Chief Executive Officer	Sell S	10.0K	-4%	$46.78	$468.7K
Mar 20, 2026	Prasad Raju KEY	Chief Financial Officer	Grant A	27.5K	New	—	$0
Mar 20, 2026	Prasad Raju KEY	Chief Financial Officer	Grant A	38.5K	New	—	$0
Mar 20, 2026	Prasad Raju KEY	Chief Financial Officer	Exercise M	6.2K	+100%	—	—
Mar 20, 2026	Prasad Raju KEY	Chief Financial Officer	Exercise M	6.2K	+48%	—	—
Mar 20, 2026	Patel Naimish	Chief Medical Officer	Grant A	38.5K	New	—	$0
Mar 20, 2026	Patel Naimish	Chief Medical Officer	Grant A	30.0K	New	—	$0
Mar 20, 2026	KASINGER JAMES R.	General Counsel and Secretary	Grant A	25.0K	New	—	$0
Mar 20, 2026	KASINGER JAMES R.	General Counsel and Secretary	Exercise M	6.2K	+109%	—	—
Mar 20, 2026	KASINGER JAMES R.	General Counsel and Secretary	Grant A	38.5K	New	—	$0
Mar 20, 2026	KASINGER JAMES R.	General Counsel and Secretary	Exercise M	6.2K	+7%	—	—
Mar 20, 2026	Kulkarni Samarth KEY	Chief Executive Officer	Grant A	114.2K	New	—	$0
Mar 20, 2026	Kulkarni Samarth KEY	Chief Executive Officer	Grant A	81.9K	New	—	$0
Mar 20, 2026	Kulkarni Samarth KEY	Chief Executive Officer	Exercise M	19.7K	+100%	—	—
Mar 20, 2026	Kulkarni Samarth KEY	Chief Executive Officer	Exercise M	19.7K	+8%	—	—
Mar 16, 2026	Prasad Raju KEY	Chief Financial Officer	Sell S	4.0K	-23%	$48.26	$194.1K
Mar 16, 2026	Prasad Raju KEY	Chief Financial Officer	Other G	750	-5%	—	$0
Mar 16, 2026	Prasad Raju KEY	Chief Financial Officer	Sell S	5.8K	-25%	$48.26	$282.2K
Mar 16, 2026	Patel Naimish	Chief Medical Officer	Sell S	3.1K	-19%	$48.26	$152.0K
Mar 16, 2026	Kulkarni Samarth KEY	Chief Executive Officer	Sell S	10.3K	-4%	$48.26	$499.4K
Mar 16, 2026	KASINGER JAMES R.	General Counsel and Secretary	Sell S	3.5K	-4%	$48.26	$166.5K
Mar 14, 2026	Prasad Raju KEY	Chief Financial Officer	Exercise M	10.0K	New	—	—
Mar 14, 2026	Prasad Raju KEY	Chief Financial Officer	Exercise M	6.9K	+50%	—	—
Mar 14, 2026	Prasad Raju KEY	Chief Financial Officer	Exercise M	10.0K	+148%	—	—
Mar 14, 2026	Prasad Raju KEY	Chief Financial Officer	Exercise M	6.9K	+41%	—	—
Mar 14, 2026	Patel Naimish	Chief Medical Officer	Exercise M	8.1K	+50%	—	—
Mar 14, 2026	Patel Naimish	Chief Medical Officer	Exercise M	8.1K	+99%	—	—
Mar 14, 2026	Kulkarni Samarth KEY	Chief Executive Officer	Exercise M	20.6K	+50%	—	—
Mar 14, 2026	Kulkarni Samarth KEY	Chief Executive Officer	Exercise M	20.6K	+9%	—	—
Mar 14, 2026	KASINGER JAMES R.	General Counsel and Secretary	Exercise M	6.9K	+50%	—	—
Mar 14, 2026	KASINGER JAMES R.	General Counsel and Secretary	Exercise M	6.9K	+8%	—	—
Mar 11, 2026	Kulkarni Samarth KEY	Chief Executive Officer	Sell S	9.8K	-4%	$52.80	$517.3K
Mar 11, 2026	KASINGER JAMES R.	General Counsel and Secretary	Sell S	2.8K	-3%	$52.80	$147.8K
Mar 10, 2026	Kulkarni Samarth KEY	Chief Executive Officer	Exercise M	19.2K	New	—	—
Mar 10, 2026	Kulkarni Samarth KEY	Chief Executive Officer	Exercise M	19.2K	+9%	—	—
Mar 10, 2026	KASINGER JAMES R.	General Counsel and Secretary	Exercise M	5.5K	New	—	—
Mar 10, 2026	KASINGER JAMES R.	General Counsel and Secretary	Exercise M	5.5K	+6%	—	—
Feb 19, 2026	KASINGER JAMES R.	General Counsel and Secretary	Sell S	2.1K	-2%	$52.58	$111.0K
Feb 19, 2026	Kulkarni Samarth KEY	Chief Executive Officer	Sell S	7.0K	-3%	$52.58	$366.3K
Feb 18, 2026	KASINGER JAMES R.	General Counsel and Secretary	Exercise M	3.8K	New	—	—
Feb 18, 2026	KASINGER JAMES R.	General Counsel and Secretary	Exercise M	3.8K	+5%	—	—
Feb 18, 2026	Kulkarni Samarth KEY	Chief Executive Officer	Exercise M	13.2K	New	—	—
Feb 18, 2026	Kulkarni Samarth KEY	Chief Executive Officer	Exercise M	13.2K	+6%	—	—
Jan 22, 2026	Kulkarni Samarth KEY 10b5-1	Chief Executive Officer	Sell S	60.0K	-31%	$60.23	$3.6M
Jan 22, 2026	Prasad Raju KEY 10b5-1	Chief Financial Officer	Exercise M	35.0K	+522%	—	$0
Jan 22, 2026	Prasad Raju KEY 10b5-1	Chief Financial Officer	Sell S	35.0K	-84%	$60.19	$2.1M
Jan 22, 2026	Prasad Raju KEY 10b5-1	Chief Financial Officer	Exercise M	35.0K	+517%	$45.15	$1.6M
Jan 20, 2026	Kulkarni Samarth KEY 10b5-1	Chief Executive Officer	Sell S	8.6K	-4%	$52.10	$446.3K
Jan 20, 2026	Kulkarni Samarth KEY 10b5-1	Chief Executive Officer	Sell S	21.4K	-10%	$51.61	$1.1M
Jan 6, 2026	Prasad Raju KEY 10b5-1	Chief Financial Officer	Exercise M	6.3K	+549%	—	$0
Jan 6, 2026	Prasad Raju KEY 10b5-1	Chief Financial Officer	Exercise M	23.4K	+44%	—	$0
Jan 6, 2026	Prasad Raju KEY 10b5-1	Chief Financial Officer	Sell S	18.9K	-52%	$60.18	$1.1M
Jan 6, 2026	Prasad Raju KEY 10b5-1	Chief Financial Officer	Sell S	5.0K	-29%	$60.00	$300.2K
Jan 6, 2026	Prasad Raju KEY 10b5-1	Chief Financial Officer	Sell S	5.8K	-46%	$60.21	$347.0K
Jan 6, 2026	Prasad Raju KEY 10b5-1	Chief Financial Officer	Exercise M	6.3K	+21%	$44.31	$280.9K
Jan 6, 2026	Prasad Raju KEY 10b5-1	Chief Financial Officer	Exercise M	23.4K	+345%	$45.15	$1.1M
Dec 22, 2025	Prasad Raju KEY 10b5-1	Chief Financial Officer	Sell S	5.5K	-41%	$56.33	$308.2K
Dec 22, 2025	Prasad Raju KEY 10b5-1	Chief Financial Officer	Sell S	1.0K	-13%	$56.89	$56.9K
Dec 22, 2025	Prasad Raju KEY 10b5-1	Chief Financial Officer	Sell S	3.5K	-21%	$55.10	$194.4K
Dec 18, 2025	Kulkarni Samarth KEY	Chief Executive Officer	Other G	30.0K	-12%	—	$0
Oct 17, 2025	Kulkarni Samarth KEY	Chief Executive Officer	Sell S	50.9K	-17%	$67.91	$3.5M
Oct 16, 2025	Kulkarni Samarth KEY	Chief Executive Officer	Exercise M	100.0K	+50%	—	—
Oct 16, 2025	Kulkarni Samarth KEY	Chief Executive Officer	Exercise M	100.0K	+49%	—	—
Oct 14, 2025	KASINGER JAMES R.	General Counsel and Secretary	Sell S	1.1K	-1%	$66.60	$71.7K
Oct 14, 2025	Kulkarni Samarth KEY	Chief Executive Officer	Sell S	4.2K	-2%	$66.60	$282.5K
Oct 13, 2025	KASINGER JAMES R.	General Counsel and Secretary	Exercise M	2.1K	New	—	—
Oct 13, 2025	KASINGER JAMES R.	General Counsel and Secretary	Exercise M	2.1K	+3%	—	—
Oct 13, 2025	Kulkarni Samarth KEY	Chief Executive Officer	Exercise M	8.3K	New	—	—
Oct 13, 2025	Kulkarni Samarth KEY	Chief Executive Officer	Exercise M	8.3K	+4%	—	—
Oct 3, 2025	Kulkarni Samarth KEY	Chief Executive Officer	Grant A	49.5K	New	—	$0
Oct 3, 2025	Prasad Raju KEY	Chief Financial Officer	Grant A	16.5K	New	—	$0
Oct 3, 2025	Patel Naimish	Chief Medical Officer	Grant A	16.5K	New	—	$0
Oct 3, 2025	KASINGER JAMES R.	General Counsel and Secretary	Grant A	16.5K	New	—	$0
Sep 17, 2025	Kulkarni Samarth KEY	Chief Executive Officer	Other G	6.0K	-3%	—	$0
Aug 18, 2025	Kulkarni Samarth KEY	Chief Executive Officer	Sell S	13.1K	-6%	$58.15	$760.7K
Aug 16, 2025	Kulkarni Samarth KEY	Chief Executive Officer	Exercise M	25.0K	New	—	—
Aug 16, 2025	Kulkarni Samarth KEY	Chief Executive Officer	Exercise M	25.0K	+13%	—	—
Aug 6, 2025	Treco Douglas A	Director	Buy P	20.0K	+1000%	$57.03	$1.1M
Jul 16, 2025	George Simeon	Director	Buy P	6.5K	+10%	$52.03	$338.7K
Jul 16, 2025	George Simeon	Director	Buy P	961.0K	+125%	$52.03	$50.0M
Jul 16, 2025	George Simeon	Director	Buy P	22.3K	+10%	$52.03	$1.2M

About CRSP insider trading

This page tracks insider transactions for CRISPR Therapeutics AG (CRSP) reported to the U.S. Securities and Exchange Commission on Form 4. Corporate insiders — directors, executive officers and beneficial owners of more than 10% of the stock — must disclose their trades within two business days. Open-market purchases (code P) and sales (code S) made at the insider's discretion are the most-watched opportunistic signals, while awards (A), option exercises (M) and tax-withholding (F) reflect compensation rather than conviction. Trades marked 10b5-1 were made under a pre-arranged plan and are considered routine. A cluster buy — several insiders buying within a short window — is historically a stronger bullish indicator than any single trade.