EIKN

insider transactions

Eikon Therapeutics, Inc. — buys & sells by directors, officers and 10% owners (SEC Form 4).

30D 90D 1Y

Cluster buy signal: 5 different insiders made open-market purchases in the last 365 days, totalling $46.1M.

Net shares · 365d

+2.6M

2.6M buy · 0 sell

Net value · 365d

$46.1M

$46.1M in · $0 out

Sentiment · 365d

Net buying

100% buying · 0% selling

Open-market trades · 365d

2.6M buy · 0 sell

Net buy / sell volume

Tap or hover the chart for daily net volume. Green = net buying, red = net selling.

All transactions

Grant·A
Mar 2, 26

Michael A Klobuchar

Chief Operating Officer

$0

87.2K sh

Own New
Grant·A
Mar 2, 26

Robert Luther Huffines

Director

$0

25.9K sh

Own New
Grant·A
Mar 2, 26

Kenneth C Frazier

Director

$0

25.9K sh

Own New
Grant·A
Mar 2, 26

Roger M Perlmutter KEY

Chief Executive Officer and D…

$0

268.2K sh

Own New
Grant·A
Mar 2, 26

Benjamin Bruno Thorner

General Counsel and Chief Bus…

$0

67.0K sh

Own New
Grant·A
Mar 2, 26

Alfred Lloyd Bowie Jr. KEY

Chief Financial Officer

$0

67.0K sh

Own New
Exercise·C
Feb 6, 26

Josh Wolfe

Director, 10% Owner

—

10.3M sh

Own New
Exercise·C
Feb 6, 26

Josh Wolfe

Director, 10% Owner

—

1.5M sh

Own New
Exercise·C
Feb 6, 26

Josh Wolfe

Director, 10% Owner

—

303.4K sh

Own New
Exercise·C
Feb 6, 26

Josh Wolfe

Director, 10% Owner

—

3.5M sh

Own New
Exercise·C
Feb 6, 26

Josh Wolfe

Director, 10% Owner

—

5.3M sh

Own New
Exercise·C
Feb 6, 26

Josh Wolfe

Director, 10% Owner

—

530.9K sh

Own New
Exercise·C
Feb 6, 26

Josh Wolfe

Director, 10% Owner

—

796.4K sh

Own New
Exercise·C
Feb 6, 26

Josh Wolfe

Director, 10% Owner

—

2.5M sh

Own New
Exercise·C
Feb 6, 26

Josh Wolfe

Director, 10% Owner

—

7.8M sh

Own New
Exercise·C
Feb 6, 26

Josh Wolfe

Director, 10% Owner

—

10.0M sh

Own New
Exercise·C
Feb 6, 26

Josh Wolfe

Director, 10% Owner

—

2.2M sh

Own +1552%
Exercise·C
Feb 6, 26

Josh Wolfe

Director, 10% Owner

—

1.2M sh

Own +829%
Exercise·C
Feb 6, 26

Josh Wolfe

Director, 10% Owner

—

2.4M sh

Own New
Exercise·C
Feb 6, 26

Lux Venture Partners V, LLC / Josh Wolfe / Peter Hebert / Lux Ventures V, L.P. / Lux Co-Invest Opportunities II, L.P. / Lux Total Opportunities, L.P.

10% Owner

—

10.3M sh

Own New
Exercise·C
Feb 6, 26

Lux Venture Partners V, LLC / Josh Wolfe / Peter Hebert / Lux Ventures V, L.P. / Lux Co-Invest Opportunities II, L.P. / Lux Total Opportunities, L.P.

10% Owner

—

1.5M sh

Own New
Exercise·C
Feb 6, 26

Lux Venture Partners V, LLC / Josh Wolfe / Peter Hebert / Lux Ventures V, L.P. / Lux Co-Invest Opportunities II, L.P. / Lux Total Opportunities, L.P.

10% Owner

—

303.4K sh

Own New
Exercise·C
Feb 6, 26

Lux Venture Partners V, LLC / Josh Wolfe / Peter Hebert / Lux Ventures V, L.P. / Lux Co-Invest Opportunities II, L.P. / Lux Total Opportunities, L.P.

10% Owner

—

3.5M sh

Own New
Exercise·C
Feb 6, 26

Lux Venture Partners V, LLC / Josh Wolfe / Peter Hebert / Lux Ventures V, L.P. / Lux Co-Invest Opportunities II, L.P. / Lux Total Opportunities, L.P.

10% Owner

—

5.3M sh

Own New
Exercise·C
Feb 6, 26

Lux Venture Partners V, LLC / Josh Wolfe / Peter Hebert / Lux Ventures V, L.P. / Lux Co-Invest Opportunities II, L.P. / Lux Total Opportunities, L.P.

10% Owner

—

530.9K sh

Own New
Exercise·C
Feb 6, 26

Lux Venture Partners V, LLC / Josh Wolfe / Peter Hebert / Lux Ventures V, L.P. / Lux Co-Invest Opportunities II, L.P. / Lux Total Opportunities, L.P.

10% Owner

—

796.4K sh

Own New
Exercise·C
Feb 6, 26

Lux Venture Partners V, LLC / Josh Wolfe / Peter Hebert / Lux Ventures V, L.P. / Lux Co-Invest Opportunities II, L.P. / Lux Total Opportunities, L.P.

10% Owner

—

2.5M sh

Own New
Exercise·C
Feb 6, 26

Lux Venture Partners V, LLC / Josh Wolfe / Peter Hebert / Lux Ventures V, L.P. / Lux Co-Invest Opportunities II, L.P. / Lux Total Opportunities, L.P.

10% Owner

—

7.8M sh

Own New
Exercise·C
Feb 6, 26

Lux Venture Partners V, LLC / Josh Wolfe / Peter Hebert / Lux Ventures V, L.P. / Lux Co-Invest Opportunities II, L.P. / Lux Total Opportunities, L.P.

10% Owner

—

10.0M sh

Own New
Exercise·C
Feb 6, 26

Lux Venture Partners V, LLC / Josh Wolfe / Peter Hebert / Lux Ventures V, L.P. / Lux Co-Invest Opportunities II, L.P. / Lux Total Opportunities, L.P.

10% Owner

—

2.2M sh

Own +1552%
Exercise·C
Feb 6, 26

Lux Venture Partners V, LLC / Josh Wolfe / Peter Hebert / Lux Ventures V, L.P. / Lux Co-Invest Opportunities II, L.P. / Lux Total Opportunities, L.P.

10% Owner

—

1.2M sh

Own +829%
Exercise·C
Feb 6, 26

Lux Venture Partners V, LLC / Josh Wolfe / Peter Hebert / Lux Ventures V, L.P. / Lux Co-Invest Opportunities II, L.P. / Lux Total Opportunities, L.P.

10% Owner

—

2.4M sh

Own New
Exercise·C
Feb 6, 26

Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson

10% Owner

—

5.1M sh

Own New
Exercise·C
Feb 6, 26

Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson

10% Owner

—

28.2K sh

Own New
Exercise·C
Feb 6, 26

Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson

10% Owner

—

827.3K sh

Own New
Exercise·C
Feb 6, 26

Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson

10% Owner

—

357.2K sh

Own New
Exercise·C
Feb 6, 26

Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson

10% Owner

—

10.5M sh

Own New
Exercise·C
Feb 6, 26

Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson

10% Owner

—

330.0K sh

Own New
Exercise·C
Feb 6, 26

Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson

10% Owner

—

9.7M sh

Own New
Buy·P
Feb 6, 26

Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson

10% Owner

$11.4M

630.9K sh · $18.00

Own +92%
Buy·P
Feb 6, 26

Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson

10% Owner

$892.0K

49.6K sh · $18.00

Own +50%
Buy·P
Feb 6, 26

Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson

10% Owner

$25.9M

1.4M sh · $18.00

Own +50%
Exercise·C
Feb 6, 26

Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson

10% Owner

—

688.3K sh

Own New
Exercise·C
Feb 6, 26

Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson

10% Owner

—

3.8K sh

Own +4%
Exercise·C
Feb 6, 26

Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson

10% Owner

—

47.9K sh

Own +101%
Exercise·C
Feb 6, 26

Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson

10% Owner

—

44.2K sh

Own +1320%
Exercise·C
Feb 6, 26

Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson

10% Owner

—

110.9K sh

Own +4%
Exercise·C
Feb 6, 26

Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson

10% Owner

—

1.4M sh

Own +103%
Exercise·C
Feb 6, 26

Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson

10% Owner

—

1.3M sh

Own +2036%
Exercise·C
Feb 6, 26

Roger M Perlmutter KEY

Chief Executive Officer and D…

—

855.5K sh

Own New
Exercise·C
Feb 6, 26

Roger M Perlmutter KEY

Chief Executive Officer and D…

—

1.3M sh

Own New
Exercise·C
Feb 6, 26

Roger M Perlmutter KEY

Chief Executive Officer and D…

—

284.9K sh

Own New
Buy·P
Feb 4, 26

Kenneth C Frazier

Director

$2.0M

111.1K sh · $18.00

Own New
Buy·P
Feb 4, 26

Josh Wolfe

Director, 10% Owner

$2.5M

138.9K sh · $18.00

Own New
Buy·P
Feb 4, 26

Lux Venture Partners V, LLC / Josh Wolfe / Peter Hebert / Lux Ventures V, L.P. / Lux Co-Invest Opportunities II, L.P. / Lux Total Opportunities, L.P.

10% Owner

$2.5M

138.9K sh · $18.00

Own New
Exercise·C
Feb 4, 26

Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A

10% Owner

$0

3.4M sh

Own New
Exercise·C
Feb 4, 26

Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A

10% Owner

$0

1.7M sh

Own New
Exercise·C
Feb 4, 26

Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A

10% Owner

$0

284.4K sh

Own New
Exercise·C
Feb 4, 26

Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A

10% Owner

$0

501.2K sh

Own New
Exercise·C
Feb 4, 26

Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A

10% Owner

$0

6.9K sh

Own New
Exercise·C
Feb 4, 26

Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A

10% Owner

$0

12.1K sh

Own New
Exercise·C
Feb 4, 26

Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A

10% Owner

$0

3.0M sh

Own New
Exercise·C
Feb 4, 26

Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A

10% Owner

$0

282.3K sh

Own New
Exercise·C
Feb 4, 26

Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A

10% Owner

$0

2.6M sh

Own New
Exercise·C
Feb 4, 26

Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A

10% Owner

$0

5.2M sh

Own New
Exercise·C
Feb 4, 26

Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A

10% Owner

$0

2.5M sh

Own New
Exercise·C
Feb 4, 26

Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A

10% Owner

$0

10.0M sh

Own New
Buy·P
Feb 4, 26

Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A

10% Owner

$1000.0K

55.6K sh · $18.00

Own +4%
Exercise·C
Feb 4, 26

Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A

10% Owner

$0

408.7K sh

Own New
Exercise·C
Feb 4, 26

Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A

10% Owner

$0

38.1K sh

Own +10%
Exercise·C
Feb 4, 26

Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A

10% Owner

$0

922 sh

Own +0%
Exercise·C
Feb 4, 26

Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A

10% Owner

$0

348.9K sh

Own New
Exercise·C
Feb 4, 26

Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A

10% Owner

$0

458.9K sh

Own +57%
Exercise·C
Feb 4, 26

Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A

10% Owner

$0

67.2K sh

Own +9%
Exercise·C
Feb 4, 26

Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A

10% Owner

$0

1.6K sh

Own +0%
Exercise·C
Feb 4, 26

Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A

10% Owner

$0

697.9K sh

Own New
Exercise·C
Feb 4, 26

Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A

10% Owner

$0

229.4K sh

Own +13%
Exercise·C
Feb 4, 26

Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A

10% Owner

$0

37.9K sh

Own +2%
Exercise·C
Feb 4, 26

Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A

10% Owner

$0

335.5K sh

Own +25%
Exercise·C
Feb 4, 26

Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A

10% Owner

$0

1.3M sh

Own New

Date▾	Insider	Role	Type	Shares	Own Δ	Price	Value
Mar 2, 2026	Michael A Klobuchar	Chief Operating Officer	Grant A	87.2K	New	—	$0
Mar 2, 2026	Robert Luther Huffines	Director	Grant A	25.9K	New	—	$0
Mar 2, 2026	Kenneth C Frazier	Director	Grant A	25.9K	New	—	$0
Mar 2, 2026	Roger M Perlmutter KEY	Chief Executive Officer and Director	Grant A	268.2K	New	—	$0
Mar 2, 2026	Benjamin Bruno Thorner	General Counsel and Chief Business Officer	Grant A	67.0K	New	—	$0
Mar 2, 2026	Alfred Lloyd Bowie Jr. KEY	Chief Financial Officer	Grant A	67.0K	New	—	$0
Feb 6, 2026	Josh Wolfe	Director, 10% Owner	Exercise C	10.3M	New	—	—
Feb 6, 2026	Josh Wolfe	Director, 10% Owner	Exercise C	1.5M	New	—	—
Feb 6, 2026	Josh Wolfe	Director, 10% Owner	Exercise C	303.4K	New	—	—
Feb 6, 2026	Josh Wolfe	Director, 10% Owner	Exercise C	3.5M	New	—	—
Feb 6, 2026	Josh Wolfe	Director, 10% Owner	Exercise C	5.3M	New	—	—
Feb 6, 2026	Josh Wolfe	Director, 10% Owner	Exercise C	530.9K	New	—	—
Feb 6, 2026	Josh Wolfe	Director, 10% Owner	Exercise C	796.4K	New	—	—
Feb 6, 2026	Josh Wolfe	Director, 10% Owner	Exercise C	2.5M	New	—	—
Feb 6, 2026	Josh Wolfe	Director, 10% Owner	Exercise C	7.8M	New	—	—
Feb 6, 2026	Josh Wolfe	Director, 10% Owner	Exercise C	10.0M	New	—	—
Feb 6, 2026	Josh Wolfe	Director, 10% Owner	Exercise C	2.2M	+1552%	—	—
Feb 6, 2026	Josh Wolfe	Director, 10% Owner	Exercise C	1.2M	+829%	—	—
Feb 6, 2026	Josh Wolfe	Director, 10% Owner	Exercise C	2.4M	New	—	—
Feb 6, 2026	Lux Venture Partners V, LLC / Josh Wolfe / Peter Hebert / Lux Ventures V, L.P. / Lux Co-Invest Opportunities II, L.P. / Lux Total Opportunities, L.P.	10% Owner	Exercise C	10.3M	New	—	—
Feb 6, 2026	Lux Venture Partners V, LLC / Josh Wolfe / Peter Hebert / Lux Ventures V, L.P. / Lux Co-Invest Opportunities II, L.P. / Lux Total Opportunities, L.P.	10% Owner	Exercise C	1.5M	New	—	—
Feb 6, 2026	Lux Venture Partners V, LLC / Josh Wolfe / Peter Hebert / Lux Ventures V, L.P. / Lux Co-Invest Opportunities II, L.P. / Lux Total Opportunities, L.P.	10% Owner	Exercise C	303.4K	New	—	—
Feb 6, 2026	Lux Venture Partners V, LLC / Josh Wolfe / Peter Hebert / Lux Ventures V, L.P. / Lux Co-Invest Opportunities II, L.P. / Lux Total Opportunities, L.P.	10% Owner	Exercise C	3.5M	New	—	—
Feb 6, 2026	Lux Venture Partners V, LLC / Josh Wolfe / Peter Hebert / Lux Ventures V, L.P. / Lux Co-Invest Opportunities II, L.P. / Lux Total Opportunities, L.P.	10% Owner	Exercise C	5.3M	New	—	—
Feb 6, 2026	Lux Venture Partners V, LLC / Josh Wolfe / Peter Hebert / Lux Ventures V, L.P. / Lux Co-Invest Opportunities II, L.P. / Lux Total Opportunities, L.P.	10% Owner	Exercise C	530.9K	New	—	—
Feb 6, 2026	Lux Venture Partners V, LLC / Josh Wolfe / Peter Hebert / Lux Ventures V, L.P. / Lux Co-Invest Opportunities II, L.P. / Lux Total Opportunities, L.P.	10% Owner	Exercise C	796.4K	New	—	—
Feb 6, 2026	Lux Venture Partners V, LLC / Josh Wolfe / Peter Hebert / Lux Ventures V, L.P. / Lux Co-Invest Opportunities II, L.P. / Lux Total Opportunities, L.P.	10% Owner	Exercise C	2.5M	New	—	—
Feb 6, 2026	Lux Venture Partners V, LLC / Josh Wolfe / Peter Hebert / Lux Ventures V, L.P. / Lux Co-Invest Opportunities II, L.P. / Lux Total Opportunities, L.P.	10% Owner	Exercise C	7.8M	New	—	—
Feb 6, 2026	Lux Venture Partners V, LLC / Josh Wolfe / Peter Hebert / Lux Ventures V, L.P. / Lux Co-Invest Opportunities II, L.P. / Lux Total Opportunities, L.P.	10% Owner	Exercise C	10.0M	New	—	—
Feb 6, 2026	Lux Venture Partners V, LLC / Josh Wolfe / Peter Hebert / Lux Ventures V, L.P. / Lux Co-Invest Opportunities II, L.P. / Lux Total Opportunities, L.P.	10% Owner	Exercise C	2.2M	+1552%	—	—
Feb 6, 2026	Lux Venture Partners V, LLC / Josh Wolfe / Peter Hebert / Lux Ventures V, L.P. / Lux Co-Invest Opportunities II, L.P. / Lux Total Opportunities, L.P.	10% Owner	Exercise C	1.2M	+829%	—	—
Feb 6, 2026	Lux Venture Partners V, LLC / Josh Wolfe / Peter Hebert / Lux Ventures V, L.P. / Lux Co-Invest Opportunities II, L.P. / Lux Total Opportunities, L.P.	10% Owner	Exercise C	2.4M	New	—	—
Feb 6, 2026	Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson	10% Owner	Exercise C	5.1M	New	—	—
Feb 6, 2026	Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson	10% Owner	Exercise C	28.2K	New	—	—
Feb 6, 2026	Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson	10% Owner	Exercise C	827.3K	New	—	—
Feb 6, 2026	Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson	10% Owner	Exercise C	357.2K	New	—	—
Feb 6, 2026	Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson	10% Owner	Exercise C	10.5M	New	—	—
Feb 6, 2026	Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson	10% Owner	Exercise C	330.0K	New	—	—
Feb 6, 2026	Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson	10% Owner	Exercise C	9.7M	New	—	—
Feb 6, 2026	Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson	10% Owner	Buy P	630.9K	+92%	$18.00	$11.4M
Feb 6, 2026	Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson	10% Owner	Buy P	49.6K	+50%	$18.00	$892.0K
Feb 6, 2026	Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson	10% Owner	Buy P	1.4M	+50%	$18.00	$25.9M
Feb 6, 2026	Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson	10% Owner	Exercise C	688.3K	New	—	—
Feb 6, 2026	Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson	10% Owner	Exercise C	3.8K	+4%	—	—
Feb 6, 2026	Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson	10% Owner	Exercise C	47.9K	+101%	—	—
Feb 6, 2026	Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson	10% Owner	Exercise C	44.2K	+1320%	—	—
Feb 6, 2026	Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson	10% Owner	Exercise C	110.9K	+4%	—	—
Feb 6, 2026	Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson	10% Owner	Exercise C	1.4M	+103%	—	—
Feb 6, 2026	Column Group IV GP, LP / Column Group IV-A, LP / Column Group IV, LP / Column Group Opportunity III, LP / Column Group Opportunity III GP, LP / TCG Opportunity III GP, LLC / Tim Kutzkey / Peter Svennilson	10% Owner	Exercise C	1.3M	+2036%	—	—
Feb 6, 2026	Roger M Perlmutter KEY	Chief Executive Officer and Director	Exercise C	855.5K	New	—	—
Feb 6, 2026	Roger M Perlmutter KEY	Chief Executive Officer and Director	Exercise C	1.3M	New	—	—
Feb 6, 2026	Roger M Perlmutter KEY	Chief Executive Officer and Director	Exercise C	284.9K	New	—	—
Feb 4, 2026	Kenneth C Frazier	Director	Buy P	111.1K	New	$18.00	$2.0M
Feb 4, 2026	Josh Wolfe	Director, 10% Owner	Buy P	138.9K	New	$18.00	$2.5M
Feb 4, 2026	Lux Venture Partners V, LLC / Josh Wolfe / Peter Hebert / Lux Ventures V, L.P. / Lux Co-Invest Opportunities II, L.P. / Lux Total Opportunities, L.P.	10% Owner	Buy P	138.9K	New	$18.00	$2.5M
Feb 4, 2026	Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A	10% Owner	Exercise C	3.4M	New	—	$0
Feb 4, 2026	Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A	10% Owner	Exercise C	1.7M	New	—	$0
Feb 4, 2026	Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A	10% Owner	Exercise C	284.4K	New	—	$0
Feb 4, 2026	Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A	10% Owner	Exercise C	501.2K	New	—	$0
Feb 4, 2026	Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A	10% Owner	Exercise C	6.9K	New	—	$0
Feb 4, 2026	Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A	10% Owner	Exercise C	12.1K	New	—	$0
Feb 4, 2026	Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A	10% Owner	Exercise C	3.0M	New	—	$0
Feb 4, 2026	Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A	10% Owner	Exercise C	282.3K	New	—	$0
Feb 4, 2026	Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A	10% Owner	Exercise C	2.6M	New	—	$0
Feb 4, 2026	Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A	10% Owner	Exercise C	5.2M	New	—	$0
Feb 4, 2026	Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A	10% Owner	Exercise C	2.5M	New	—	$0
Feb 4, 2026	Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A	10% Owner	Exercise C	10.0M	New	—	$0
Feb 4, 2026	Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A	10% Owner	Buy P	55.6K	+4%	$18.00	$1000.0K
Feb 4, 2026	Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A	10% Owner	Exercise C	408.7K	New	—	$0
Feb 4, 2026	Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A	10% Owner	Exercise C	38.1K	+10%	—	$0
Feb 4, 2026	Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A	10% Owner	Exercise C	922	+0%	—	$0
Feb 4, 2026	Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A	10% Owner	Exercise C	348.9K	New	—	$0
Feb 4, 2026	Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A	10% Owner	Exercise C	458.9K	+57%	—	$0
Feb 4, 2026	Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A	10% Owner	Exercise C	67.2K	+9%	—	$0
Feb 4, 2026	Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A	10% Owner	Exercise C	1.6K	+0%	—	$0
Feb 4, 2026	Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A	10% Owner	Exercise C	697.9K	New	—	$0
Feb 4, 2026	Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A	10% Owner	Exercise C	229.4K	+13%	—	$0
Feb 4, 2026	Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A	10% Owner	Exercise C	37.9K	+2%	—	$0
Feb 4, 2026	Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A	10% Owner	Exercise C	335.5K	+25%	—	$0
Feb 4, 2026	Foresite Capital Management IV, LLC / Foresite Capital Fund IV, L.P. / Foresite Capital Management V, LLC / Foresite Capital Fund V, L.P. / Foresite Capital Opportunity Management V, LLC / Foresite Capital Opportunity Fund V, L.P. / Foresite Capital VI-A	10% Owner	Exercise C	1.3M	New	—	$0

About EIKN insider trading

This page tracks insider transactions for Eikon Therapeutics, Inc. (EIKN) reported to the U.S. Securities and Exchange Commission on Form 4. Corporate insiders — directors, executive officers and beneficial owners of more than 10% of the stock — must disclose their trades within two business days. Open-market purchases (code P) and sales (code S) made at the insider's discretion are the most-watched opportunistic signals, while awards (A), option exercises (M) and tax-withholding (F) reflect compensation rather than conviction. Trades marked 10b5-1 were made under a pre-arranged plan and are considered routine. A cluster buy — several insiders buying within a short window — is historically a stronger bullish indicator than any single trade.