KYMR

insider transactions

Kymera Therapeutics, Inc. — buys & sells by directors, officers and 10% owners (SEC Form 4).

30D 90D 1Y

Net shares · 365d

-314.1K

0 buy · 314.1K sell

Net value · 365d

-$25.8M

$0 in · $25.8M out

Sentiment · 365d

Net selling

0% buying · 100% selling

Open-market trades · 365d

0 buy · 314.1K sell

Net buy / sell volume

Tap or hover the chart for daily net volume. Green = net buying, red = net selling.

All transactions

Exercise·M
Jun 2, 26

Bruce N. Jacobs KEY

Chief Financial Officer

$0

12.7K sh

Own New
Exercise·M
Jun 2, 26

Bruce N. Jacobs KEY

Chief Financial Officer

$26.3K

12.7K sh · $2.08

Own +5%
Sell·S
May 27, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$49.2K

600 sh · $82.08

Own -1%
Sell·S
May 27, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$299.8K

3.7K sh · $81.50

Own -8%
Sell·S
May 26, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$44.5K

551 sh · $80.71

Own -1%
Sell·S
May 26, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$360.1K

4.5K sh · $80.02

Own -8%
Sell·S
May 26, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$301.7K

3.8K sh · $79.39

Own -7%
Sell·S
May 26, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$25.7K

324 sh · $79.17

Own -1%
Sell·S
May 26, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$292.3K

3.7K sh · $78.36

Own -6%
Exercise·M
May 19, 26

Pamela Esposito

Director

$0

1.0K sh

Own +12%
Exercise·M
May 19, 26

Pamela Esposito

Director

$31.2K

1.0K sh · $31.20

Own New
Exercise·M
May 18, 26

Bruce N. Jacobs KEY

Chief Financial Officer

$0

15.0K sh

Own New
Exercise·M
May 18, 26

Bruce N. Jacobs KEY

Chief Financial Officer

$31.2K

15.0K sh · $2.08

Own +6%
Exercise·M
May 11, 26

Elena Ridloff

Director · 10b5-1

$0

3.0K sh

Own +30%
Sell·S
May 11, 26

Elena Ridloff

Director · 10b5-1

$261.0K

3.0K sh · $87.00

Own -100%
Exercise·M
May 11, 26

Elena Ridloff

Director · 10b5-1

$93.6K

3.0K sh · $31.20

Own New
Exercise·M
Apr 29, 26

Nello Mainolfi KEY

Chief Executive Officer · 10b5-1

$0

30.0K sh

Own +16%
Sell·S
Apr 29, 26

Nello Mainolfi KEY

Chief Executive Officer · 10b5-1

$77.2K

936 sh · $82.45

Own -0%
Sell·S
Apr 29, 26

Nello Mainolfi KEY

Chief Executive Officer · 10b5-1

$985.2K

12.1K sh · $81.70

Own -2%
Sell·S
Apr 29, 26

Nello Mainolfi KEY

Chief Executive Officer · 10b5-1

$1.4M

17.0K sh · $80.74

Own -2%
Exercise·M
Apr 29, 26

Nello Mainolfi KEY

Chief Executive Officer · 10b5-1

$62.4K

30.0K sh · $2.08

Own +5%
Exercise·M
Apr 22, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$0

200 sh

Own +0%
Exercise·M
Apr 22, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$0

100 sh

Own +0%
Sell·S
Apr 22, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$27.0K

300 sh · $90.00

Own -0%
Exercise·M
Apr 22, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$8.7K

200 sh · $43.50

Own +0%
Exercise·M
Apr 22, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$3.0K

100 sh · $30.17

Own +0%
Exercise·M
Apr 15, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$0

1.3K sh

Own +2%
Sell·S
Apr 15, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$117.0K

1.3K sh · $90.00

Own -2%
Exercise·M
Apr 15, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$56.5K

1.3K sh · $43.50

Own +2%
Sell·S
Apr 14, 26

Noah Goodman

Chief Business Officer · 10b5-1

$121.2K

1.3K sh · $90.00

Own -3%
Exercise·M
Apr 14, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$0

785 sh

Own +1%
Exercise·M
Apr 14, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$0

4.5K sh

Own +11%
Sell·S
Apr 14, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$472.6K

5.3K sh · $90.00

Own -8%
Exercise·M
Apr 14, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$34.1K

785 sh · $43.50

Own +1%
Exercise·M
Apr 14, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$134.7K

4.5K sh · $30.17

Own +7%
Sell·S
Apr 10, 26

Noah Goodman

Chief Business Officer · 10b5-1

$174.7K

2.0K sh · $87.35

Own -4%
Exercise·M
Apr 9, 26

Noah Goodman

Chief Business Officer · 10b5-1

$0

2.5K sh

Own +3%
Sell·S
Apr 9, 26

Noah Goodman

Chief Business Officer · 10b5-1

$222.5K

2.5K sh · $89.00

Own -4%
Sell·S
Apr 9, 26

Noah Goodman

Chief Business Officer · 10b5-1

$232.6K

2.7K sh · $87.11

Own -5%
Sell·S
Apr 9, 26

Noah Goodman

Chief Business Officer · 10b5-1

$268.0K

3.1K sh · $86.62

Own -5%
Exercise·M
Apr 9, 26

Noah Goodman

Chief Business Officer · 10b5-1

$52.6K

2.5K sh · $21.05

Own +4%
Exercise·M
Apr 1, 26

Elena Ridloff

Director · 10b5-1

$0

4.6K sh

Own New
Sell·S
Apr 1, 26

Elena Ridloff

Director · 10b5-1

$103.3K

1.2K sh · $86.05

Own -100%
Sell·S
Apr 1, 26

Elena Ridloff

Director · 10b5-1

$289.7K

3.4K sh · $85.19

Own -74%
Exercise·M
Apr 1, 26

Elena Ridloff

Director · 10b5-1

$65.2K

4.6K sh · $14.18

Own New
Exercise·M
Apr 1, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$0

14.6K sh

Own +27%
Sell·S
Apr 1, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$94.7K

1.1K sh · $86.05

Own -2%
Sell·S
Apr 1, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$1.2M

13.5K sh · $85.41

Own -18%
Exercise·M
Apr 1, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$433.9K

14.6K sh · $29.64

Own +24%
Exercise·M
Mar 31, 26

Elena Ridloff

Director · 10b5-1

$0

7.4K sh

Own New
Sell·S
Mar 31, 26

Elena Ridloff

Director · 10b5-1

$631.7K

7.4K sh · $85.37

Own -100%
Exercise·M
Mar 31, 26

Elena Ridloff

Director · 10b5-1

$104.9K

7.4K sh · $14.18

Own New
Exercise·M
Mar 31, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$0

7.6K sh

Own +10%
Sell·S
Mar 31, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$648.9K

7.6K sh · $85.38

Own -11%
Exercise·M
Mar 31, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$225.3K

7.6K sh · $29.64

Own +12%
Exercise·M
Mar 25, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$0

24.7K sh

Own +37%
Sell·S
Mar 25, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$2.0M

24.7K sh · $80.26

Own -29%
Exercise·M
Mar 25, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$732.9K

24.7K sh · $29.64

Own +40%
Exercise·M
Mar 23, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$0

84.4K sh

Own +271%
Sell·S
Mar 23, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$96.1K

1.2K sh · $80.05

Own -2%
Sell·S
Mar 23, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$487.6K

6.1K sh · $79.87

Own -9%
Sell·S
Mar 23, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$644.0K

8.2K sh · $78.40

Own -11%
Sell·S
Mar 23, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$4.1M

53.0K sh · $77.21

Own -41%
Sell·S
Mar 23, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$1.7M

22.8K sh · $76.73

Own -15%
Exercise·M
Mar 23, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$2.5M

84.4K sh · $29.64

Own +124%
Exercise·M
Mar 20, 26

Pamela Esposito

Director · 10b5-1

$0

2.5K sh

Own New
Sell·S
Mar 20, 26

Pamela Esposito

Director · 10b5-1

$95.9K

1.2K sh · $79.94

Own -100%
Sell·S
Mar 20, 26

Pamela Esposito

Director · 10b5-1

$47.5K

600 sh · $79.24

Own -33%
Sell·S
Mar 20, 26

Pamela Esposito

Director · 10b5-1

$54.4K

700 sh · $77.71

Own -28%
Exercise·M
Mar 20, 26

Pamela Esposito

Director · 10b5-1

$122.8K

2.5K sh · $49.10

Own New
Exercise·M
Mar 11, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$0

20.0K sh

Own +49%
Sell·S
Mar 11, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$930.2K

11.1K sh · $83.72

Own -14%
Sell·S
Mar 11, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$1.1M

12.9K sh · $83.10

Own -14%
Sell·S
Mar 11, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$145.0K

1.8K sh · $82.13

Own -2%
Exercise·M
Mar 11, 26

Jeremy G Chadwick

Chief Operating Officer · 10b5-1

$870.0K

20.0K sh · $43.50

Own +27%
Sell·S
Mar 4, 26

Bruce N. Jacobs KEY

Chief Financial Officer

$38.7K

447 sh · $86.62

Own -0%
Sell·S
Mar 4, 26

Bruce N. Jacobs KEY

Chief Financial Officer

$123.3K

1.4K sh · $85.78

Own -1%
Sell·S
Mar 4, 26

Bruce N. Jacobs KEY

Chief Financial Officer

$214.2K

2.5K sh · $85.04

Own -1%
Sell·S
Mar 4, 26

Bruce N. Jacobs KEY

Chief Financial Officer

$41.3K

492 sh · $84.00

Own -0%
Sell·S
Mar 4, 26

Jared Gollob

Chief Medical Officer

$38.7K

447 sh · $86.62

Own -0%
Sell·S
Mar 4, 26

Jared Gollob

Chief Medical Officer

$123.3K

1.4K sh · $85.78

Own -1%
Sell·S
Mar 4, 26

Jared Gollob

Chief Medical Officer

$214.2K

2.5K sh · $85.04

Own -2%
Sell·S
Mar 4, 26

Jared Gollob

Chief Medical Officer

$41.3K

492 sh · $84.00

Own -0%
Sell·S
Mar 4, 26

Jeremy G Chadwick

Chief Operating Officer

$31.0K

358 sh · $86.62

Own -0%
Sell·S
Mar 4, 26

Jeremy G Chadwick

Chief Operating Officer

$98.6K

1.1K sh · $85.78

Own -2%
Sell·S
Mar 4, 26

Jeremy G Chadwick

Chief Operating Officer

$171.5K

2.0K sh · $85.04

Own -3%
Sell·S
Mar 4, 26

Jeremy G Chadwick

Chief Operating Officer

$33.1K

394 sh · $84.00

Own -1%
Grant·A
Mar 2, 26

Nello Mainolfi KEY

Chief Executive Officer

$0

215.0K sh

Own New
Grant·A
Mar 2, 26

Bruce N. Jacobs KEY

Chief Financial Officer

$0

35.3K sh

Own New
Sell·S
Mar 2, 26

Bruce N. Jacobs KEY

Chief Financial Officer

$368.8K

4.1K sh · $89.66

Own -2%
Sell·S
Mar 2, 26

Bruce N. Jacobs KEY

Chief Financial Officer

$126.0K

1.4K sh · $88.50

Own -1%
Sell·S
Mar 2, 26

Bruce N. Jacobs KEY

Chief Financial Officer

$178.9K

2.0K sh · $87.75

Own -1%
Grant·A
Mar 2, 26

Bruce N. Jacobs KEY

Chief Financial Officer

$0

17.6K sh

Own +8%
Grant·A
Mar 2, 26

Noah Goodman

Chief Business Officer

$0

18.4K sh

Own New
Grant·A
Mar 2, 26

Noah Goodman

Chief Business Officer

$0

9.2K sh

Own +18%
Grant·A
Mar 2, 26

Jared Gollob

Chief Medical Officer

$0

35.3K sh

Own New
Sell·S
Mar 2, 26

Jared Gollob

Chief Medical Officer

$273.3K

3.0K sh · $89.66

Own -2%
Sell·S
Mar 2, 26

Jared Gollob

Chief Medical Officer

$93.4K

1.1K sh · $88.50

Own -1%
Sell·S
Mar 2, 26

Jared Gollob

Chief Medical Officer

$132.5K

1.5K sh · $87.75

Own -1%
Grant·A
Mar 2, 26

Jared Gollob

Chief Medical Officer

$0

17.6K sh

Own +16%
Grant·A
Mar 2, 26

Jeremy G Chadwick

Chief Operating Officer

$0

25.1K sh

Own New
Sell·S
Mar 2, 26

Jeremy G Chadwick

Chief Operating Officer

$99.3K

1.1K sh · $89.66

Own -1%
Sell·S
Mar 2, 26

Jeremy G Chadwick

Chief Operating Officer

$33.9K

383 sh · $88.50

Own -0%
Sell·S
Mar 2, 26

Jeremy G Chadwick

Chief Operating Officer

$48.2K

549 sh · $87.75

Own -1%
Grant·A
Mar 2, 26

Jeremy G Chadwick

Chief Operating Officer

$0

12.6K sh

Own +19%
Grant·A
Mar 2, 26

Brian Adams

Chief Legal Officer

$0

8.2K sh

Own New
Grant·A
Mar 2, 26

Brian Adams

Chief Legal Officer

$0

4.1K sh

Own +8%
Exercise·M
Feb 25, 26

Nello Mainolfi KEY

Chief Executive Officer · 10b5-1

$0

30.0K sh

Own +14%
Sell·S
Feb 25, 26

Nello Mainolfi KEY

Chief Executive Officer · 10b5-1

$748

8 sh · $93.49

Own -0%
Sell·S
Feb 25, 26

Nello Mainolfi KEY

Chief Executive Officer · 10b5-1

$139.3K

1.5K sh · $92.81

Own -0%
Sell·S
Feb 25, 26

Nello Mainolfi KEY

Chief Executive Officer · 10b5-1

$302.2K

3.3K sh · $91.76

Own -0%
Sell·S
Feb 25, 26

Nello Mainolfi KEY

Chief Executive Officer · 10b5-1

$491.2K

5.4K sh · $90.39

Own -1%
Sell·S
Feb 25, 26

Nello Mainolfi KEY

Chief Executive Officer · 10b5-1

$1.8M

19.8K sh · $89.78

Own -3%
Exercise·M
Feb 25, 26

Nello Mainolfi KEY

Chief Executive Officer · 10b5-1

$62.4K

30.0K sh · $2.08

Own +5%
Exercise·M
Feb 20, 26

Pamela Esposito

Director · 10b5-1

$0

2.5K sh

Own New
Sell·S
Feb 20, 26

Pamela Esposito

Director · 10b5-1

$52.9K

600 sh · $88.10

Own -100%
Sell·S
Feb 20, 26

Pamela Esposito

Director · 10b5-1

$165.4K

1.9K sh · $87.06

Own -76%
Exercise·M
Feb 20, 26

Pamela Esposito

Director · 10b5-1

$122.8K

2.5K sh · $49.10

Own New
Exercise·M
Jan 20, 26

Pamela Esposito

Director · 10b5-1

$0

2.5K sh

Own +100%
Exercise·M
Jan 20, 26

Pamela Esposito

Director · 10b5-1

$0

3.0K sh

Own +43%
Sell·S
Jan 20, 26

Pamela Esposito

Director · 10b5-1

$13.7K

200 sh · $68.52

Own -100%
Sell·S
Jan 20, 26

Pamela Esposito

Director · 10b5-1

$333.1K

4.9K sh · $67.99

Own -96%
Sell·S
Jan 20, 26

Pamela Esposito

Director · 10b5-1

$26.7K

400 sh · $66.68

Own -7%
Exercise·M
Jan 20, 26

Pamela Esposito

Director · 10b5-1

$122.8K

2.5K sh · $49.10

Own +83%
Exercise·M
Jan 20, 26

Pamela Esposito

Director · 10b5-1

$93.6K

3.0K sh · $31.20

Own New
Exercise·M
Jan 5, 26

Nello Mainolfi KEY

Chief Executive Officer

$0

3.1K sh

Own +1%
Exercise·M
Jan 5, 26

Nello Mainolfi KEY

Chief Executive Officer

$100.0K

3.1K sh · $32.07

Own +0%

Date▾	Insider	Role	Type	Shares	Own Δ	Price	Value
Jun 2, 2026	Bruce N. Jacobs KEY	Chief Financial Officer	Exercise M	12.7K	New	—	$0
Jun 2, 2026	Bruce N. Jacobs KEY	Chief Financial Officer	Exercise M	12.7K	+5%	$2.08	$26.3K
May 27, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Sell S	600	-1%	$82.08	$49.2K
May 27, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Sell S	3.7K	-8%	$81.50	$299.8K
May 26, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Sell S	551	-1%	$80.71	$44.5K
May 26, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Sell S	4.5K	-8%	$80.02	$360.1K
May 26, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Sell S	3.8K	-7%	$79.39	$301.7K
May 26, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Sell S	324	-1%	$79.17	$25.7K
May 26, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Sell S	3.7K	-6%	$78.36	$292.3K
May 19, 2026	Pamela Esposito	Director	Exercise M	1.0K	+12%	—	$0
May 19, 2026	Pamela Esposito	Director	Exercise M	1.0K	New	$31.20	$31.2K
May 18, 2026	Bruce N. Jacobs KEY	Chief Financial Officer	Exercise M	15.0K	New	—	$0
May 18, 2026	Bruce N. Jacobs KEY	Chief Financial Officer	Exercise M	15.0K	+6%	$2.08	$31.2K
May 11, 2026	Elena Ridloff 10b5-1	Director	Exercise M	3.0K	+30%	—	$0
May 11, 2026	Elena Ridloff 10b5-1	Director	Sell S	3.0K	-100%	$87.00	$261.0K
May 11, 2026	Elena Ridloff 10b5-1	Director	Exercise M	3.0K	New	$31.20	$93.6K
Apr 29, 2026	Nello Mainolfi KEY 10b5-1	Chief Executive Officer	Exercise M	30.0K	+16%	—	$0
Apr 29, 2026	Nello Mainolfi KEY 10b5-1	Chief Executive Officer	Sell S	936	-0%	$82.45	$77.2K
Apr 29, 2026	Nello Mainolfi KEY 10b5-1	Chief Executive Officer	Sell S	12.1K	-2%	$81.70	$985.2K
Apr 29, 2026	Nello Mainolfi KEY 10b5-1	Chief Executive Officer	Sell S	17.0K	-2%	$80.74	$1.4M
Apr 29, 2026	Nello Mainolfi KEY 10b5-1	Chief Executive Officer	Exercise M	30.0K	+5%	$2.08	$62.4K
Apr 22, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Exercise M	200	+0%	—	$0
Apr 22, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Exercise M	100	+0%	—	$0
Apr 22, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Sell S	300	-0%	$90.00	$27.0K
Apr 22, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Exercise M	200	+0%	$43.50	$8.7K
Apr 22, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Exercise M	100	+0%	$30.17	$3.0K
Apr 15, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Exercise M	1.3K	+2%	—	$0
Apr 15, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Sell S	1.3K	-2%	$90.00	$117.0K
Apr 15, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Exercise M	1.3K	+2%	$43.50	$56.5K
Apr 14, 2026	Noah Goodman 10b5-1	Chief Business Officer	Sell S	1.3K	-3%	$90.00	$121.2K
Apr 14, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Exercise M	785	+1%	—	$0
Apr 14, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Exercise M	4.5K	+11%	—	$0
Apr 14, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Sell S	5.3K	-8%	$90.00	$472.6K
Apr 14, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Exercise M	785	+1%	$43.50	$34.1K
Apr 14, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Exercise M	4.5K	+7%	$30.17	$134.7K
Apr 10, 2026	Noah Goodman 10b5-1	Chief Business Officer	Sell S	2.0K	-4%	$87.35	$174.7K
Apr 9, 2026	Noah Goodman 10b5-1	Chief Business Officer	Exercise M	2.5K	+3%	—	$0
Apr 9, 2026	Noah Goodman 10b5-1	Chief Business Officer	Sell S	2.5K	-4%	$89.00	$222.5K
Apr 9, 2026	Noah Goodman 10b5-1	Chief Business Officer	Sell S	2.7K	-5%	$87.11	$232.6K
Apr 9, 2026	Noah Goodman 10b5-1	Chief Business Officer	Sell S	3.1K	-5%	$86.62	$268.0K
Apr 9, 2026	Noah Goodman 10b5-1	Chief Business Officer	Exercise M	2.5K	+4%	$21.05	$52.6K
Apr 1, 2026	Elena Ridloff 10b5-1	Director	Exercise M	4.6K	New	—	$0
Apr 1, 2026	Elena Ridloff 10b5-1	Director	Sell S	1.2K	-100%	$86.05	$103.3K
Apr 1, 2026	Elena Ridloff 10b5-1	Director	Sell S	3.4K	-74%	$85.19	$289.7K
Apr 1, 2026	Elena Ridloff 10b5-1	Director	Exercise M	4.6K	New	$14.18	$65.2K
Apr 1, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Exercise M	14.6K	+27%	—	$0
Apr 1, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Sell S	1.1K	-2%	$86.05	$94.7K
Apr 1, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Sell S	13.5K	-18%	$85.41	$1.2M
Apr 1, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Exercise M	14.6K	+24%	$29.64	$433.9K
Mar 31, 2026	Elena Ridloff 10b5-1	Director	Exercise M	7.4K	New	—	$0
Mar 31, 2026	Elena Ridloff 10b5-1	Director	Sell S	7.4K	-100%	$85.37	$631.7K
Mar 31, 2026	Elena Ridloff 10b5-1	Director	Exercise M	7.4K	New	$14.18	$104.9K
Mar 31, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Exercise M	7.6K	+10%	—	$0
Mar 31, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Sell S	7.6K	-11%	$85.38	$648.9K
Mar 31, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Exercise M	7.6K	+12%	$29.64	$225.3K
Mar 25, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Exercise M	24.7K	+37%	—	$0
Mar 25, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Sell S	24.7K	-29%	$80.26	$2.0M
Mar 25, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Exercise M	24.7K	+40%	$29.64	$732.9K
Mar 23, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Exercise M	84.4K	+271%	—	$0
Mar 23, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Sell S	1.2K	-2%	$80.05	$96.1K
Mar 23, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Sell S	6.1K	-9%	$79.87	$487.6K
Mar 23, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Sell S	8.2K	-11%	$78.40	$644.0K
Mar 23, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Sell S	53.0K	-41%	$77.21	$4.1M
Mar 23, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Sell S	22.8K	-15%	$76.73	$1.7M
Mar 23, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Exercise M	84.4K	+124%	$29.64	$2.5M
Mar 20, 2026	Pamela Esposito 10b5-1	Director	Exercise M	2.5K	New	—	$0
Mar 20, 2026	Pamela Esposito 10b5-1	Director	Sell S	1.2K	-100%	$79.94	$95.9K
Mar 20, 2026	Pamela Esposito 10b5-1	Director	Sell S	600	-33%	$79.24	$47.5K
Mar 20, 2026	Pamela Esposito 10b5-1	Director	Sell S	700	-28%	$77.71	$54.4K
Mar 20, 2026	Pamela Esposito 10b5-1	Director	Exercise M	2.5K	New	$49.10	$122.8K
Mar 11, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Exercise M	20.0K	+49%	—	$0
Mar 11, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Sell S	11.1K	-14%	$83.72	$930.2K
Mar 11, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Sell S	12.9K	-14%	$83.10	$1.1M
Mar 11, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Sell S	1.8K	-2%	$82.13	$145.0K
Mar 11, 2026	Jeremy G Chadwick 10b5-1	Chief Operating Officer	Exercise M	20.0K	+27%	$43.50	$870.0K
Mar 4, 2026	Bruce N. Jacobs KEY	Chief Financial Officer	Sell S	447	-0%	$86.62	$38.7K
Mar 4, 2026	Bruce N. Jacobs KEY	Chief Financial Officer	Sell S	1.4K	-1%	$85.78	$123.3K
Mar 4, 2026	Bruce N. Jacobs KEY	Chief Financial Officer	Sell S	2.5K	-1%	$85.04	$214.2K
Mar 4, 2026	Bruce N. Jacobs KEY	Chief Financial Officer	Sell S	492	-0%	$84.00	$41.3K
Mar 4, 2026	Jared Gollob	Chief Medical Officer	Sell S	447	-0%	$86.62	$38.7K
Mar 4, 2026	Jared Gollob	Chief Medical Officer	Sell S	1.4K	-1%	$85.78	$123.3K
Mar 4, 2026	Jared Gollob	Chief Medical Officer	Sell S	2.5K	-2%	$85.04	$214.2K
Mar 4, 2026	Jared Gollob	Chief Medical Officer	Sell S	492	-0%	$84.00	$41.3K
Mar 4, 2026	Jeremy G Chadwick	Chief Operating Officer	Sell S	358	-0%	$86.62	$31.0K
Mar 4, 2026	Jeremy G Chadwick	Chief Operating Officer	Sell S	1.1K	-2%	$85.78	$98.6K
Mar 4, 2026	Jeremy G Chadwick	Chief Operating Officer	Sell S	2.0K	-3%	$85.04	$171.5K
Mar 4, 2026	Jeremy G Chadwick	Chief Operating Officer	Sell S	394	-1%	$84.00	$33.1K
Mar 2, 2026	Nello Mainolfi KEY	Chief Executive Officer	Grant A	215.0K	New	—	$0
Mar 2, 2026	Bruce N. Jacobs KEY	Chief Financial Officer	Grant A	35.3K	New	—	$0
Mar 2, 2026	Bruce N. Jacobs KEY	Chief Financial Officer	Sell S	4.1K	-2%	$89.66	$368.8K
Mar 2, 2026	Bruce N. Jacobs KEY	Chief Financial Officer	Sell S	1.4K	-1%	$88.50	$126.0K
Mar 2, 2026	Bruce N. Jacobs KEY	Chief Financial Officer	Sell S	2.0K	-1%	$87.75	$178.9K
Mar 2, 2026	Bruce N. Jacobs KEY	Chief Financial Officer	Grant A	17.6K	+8%	—	$0
Mar 2, 2026	Noah Goodman	Chief Business Officer	Grant A	18.4K	New	—	$0
Mar 2, 2026	Noah Goodman	Chief Business Officer	Grant A	9.2K	+18%	—	$0
Mar 2, 2026	Jared Gollob	Chief Medical Officer	Grant A	35.3K	New	—	$0
Mar 2, 2026	Jared Gollob	Chief Medical Officer	Sell S	3.0K	-2%	$89.66	$273.3K
Mar 2, 2026	Jared Gollob	Chief Medical Officer	Sell S	1.1K	-1%	$88.50	$93.4K
Mar 2, 2026	Jared Gollob	Chief Medical Officer	Sell S	1.5K	-1%	$87.75	$132.5K
Mar 2, 2026	Jared Gollob	Chief Medical Officer	Grant A	17.6K	+16%	—	$0
Mar 2, 2026	Jeremy G Chadwick	Chief Operating Officer	Grant A	25.1K	New	—	$0
Mar 2, 2026	Jeremy G Chadwick	Chief Operating Officer	Sell S	1.1K	-1%	$89.66	$99.3K
Mar 2, 2026	Jeremy G Chadwick	Chief Operating Officer	Sell S	383	-0%	$88.50	$33.9K
Mar 2, 2026	Jeremy G Chadwick	Chief Operating Officer	Sell S	549	-1%	$87.75	$48.2K
Mar 2, 2026	Jeremy G Chadwick	Chief Operating Officer	Grant A	12.6K	+19%	—	$0
Mar 2, 2026	Brian Adams	Chief Legal Officer	Grant A	8.2K	New	—	$0
Mar 2, 2026	Brian Adams	Chief Legal Officer	Grant A	4.1K	+8%	—	$0
Feb 25, 2026	Nello Mainolfi KEY 10b5-1	Chief Executive Officer	Exercise M	30.0K	+14%	—	$0
Feb 25, 2026	Nello Mainolfi KEY 10b5-1	Chief Executive Officer	Sell S	8	-0%	$93.49	$748
Feb 25, 2026	Nello Mainolfi KEY 10b5-1	Chief Executive Officer	Sell S	1.5K	-0%	$92.81	$139.3K
Feb 25, 2026	Nello Mainolfi KEY 10b5-1	Chief Executive Officer	Sell S	3.3K	-0%	$91.76	$302.2K
Feb 25, 2026	Nello Mainolfi KEY 10b5-1	Chief Executive Officer	Sell S	5.4K	-1%	$90.39	$491.2K
Feb 25, 2026	Nello Mainolfi KEY 10b5-1	Chief Executive Officer	Sell S	19.8K	-3%	$89.78	$1.8M
Feb 25, 2026	Nello Mainolfi KEY 10b5-1	Chief Executive Officer	Exercise M	30.0K	+5%	$2.08	$62.4K
Feb 20, 2026	Pamela Esposito 10b5-1	Director	Exercise M	2.5K	New	—	$0
Feb 20, 2026	Pamela Esposito 10b5-1	Director	Sell S	600	-100%	$88.10	$52.9K
Feb 20, 2026	Pamela Esposito 10b5-1	Director	Sell S	1.9K	-76%	$87.06	$165.4K
Feb 20, 2026	Pamela Esposito 10b5-1	Director	Exercise M	2.5K	New	$49.10	$122.8K
Jan 20, 2026	Pamela Esposito 10b5-1	Director	Exercise M	2.5K	+100%	—	$0
Jan 20, 2026	Pamela Esposito 10b5-1	Director	Exercise M	3.0K	+43%	—	$0
Jan 20, 2026	Pamela Esposito 10b5-1	Director	Sell S	200	-100%	$68.52	$13.7K
Jan 20, 2026	Pamela Esposito 10b5-1	Director	Sell S	4.9K	-96%	$67.99	$333.1K
Jan 20, 2026	Pamela Esposito 10b5-1	Director	Sell S	400	-7%	$66.68	$26.7K
Jan 20, 2026	Pamela Esposito 10b5-1	Director	Exercise M	2.5K	+83%	$49.10	$122.8K
Jan 20, 2026	Pamela Esposito 10b5-1	Director	Exercise M	3.0K	New	$31.20	$93.6K
Jan 5, 2026	Nello Mainolfi KEY	Chief Executive Officer	Exercise M	3.1K	+1%	—	$0
Jan 5, 2026	Nello Mainolfi KEY	Chief Executive Officer	Exercise M	3.1K	+0%	$32.07	$100.0K

About KYMR insider trading

This page tracks insider transactions for Kymera Therapeutics, Inc. (KYMR) reported to the U.S. Securities and Exchange Commission on Form 4. Corporate insiders — directors, executive officers and beneficial owners of more than 10% of the stock — must disclose their trades within two business days. Open-market purchases (code P) and sales (code S) made at the insider's discretion are the most-watched opportunistic signals, while awards (A), option exercises (M) and tax-withholding (F) reflect compensation rather than conviction. Trades marked 10b5-1 were made under a pre-arranged plan and are considered routine. A cluster buy — several insiders buying within a short window — is historically a stronger bullish indicator than any single trade.