PRAX

insider transactions

Praxis Precision Medicines, Inc. — buys & sells by directors, officers and 10% owners (SEC Form 4).

30D 90D 1Y

No open-market buys or sells this period. The trades below are grants, option exercises and gifts, which carry no market price.

Net buy / sell volume

Tap or hover the chart for daily net volume. Green = net buying, red = net selling.

All transactions

Grant·A
Jun 12, 26

Dean J Mitchell

Director

$0

13.4K sh

Own New
Grant·A
Jun 12, 26

Dean J Mitchell

Director

$0

6.0K sh

Own +7%
Grant·A
Jun 10, 26

William D Young

Director

$0

648 sh

Own New
Grant·A
Jun 10, 26

William D Young

Director

$0

1.4K sh

Own +72%
Grant·A
Jun 10, 26

Dean J Mitchell

Director

$0

648 sh

Own New
Grant·A
Jun 10, 26

Dean J Mitchell

Director

$0

1.4K sh

Own +8%
Grant·A
Jun 10, 26

Jeffrey B Kindler

Director

$0

648 sh

Own New
Grant·A
Jun 10, 26

Jeffrey B Kindler

Director

$0

1.4K sh

Own +118%
Grant·A
Jun 10, 26

Jill Desimone

Director

$0

648 sh

Own New
Grant·A
Jun 10, 26

Jill Desimone

Director

$0

1.4K sh

Own +142%
Grant·A
Jun 10, 26

Merit Ester Cudkowicz

Director

$0

648 sh

Own New
Grant·A
Jun 10, 26

Merit Ester Cudkowicz

Director

$0

1.4K sh

Own New
Grant·A
Jun 10, 26

Jeffrey Chodakewitz

Director

$0

648 sh

Own New
Grant·A
Jun 10, 26

Jeffrey Chodakewitz

Director

$0

1.4K sh

Own New
Grant·A
Jun 10, 26

Stuart A Arbuckle

Director

$0

648 sh

Own New
Grant·A
Jun 10, 26

Stuart A Arbuckle

Director

$0

1.4K sh

Own +118%
Grant·A
May 14, 26

Megan Sniecinski

Chief Operating Officer

$14.9K

89 sh · $167.94

Own +0%
Grant·A
May 14, 26

Marcio Souza KEY

Chief Executive Officer

$21.2K

126 sh · $167.94

Own +0%
Grant·A
May 14, 26

Alex Nemiroff

General Counsel and Secretary

$13.1K

78 sh · $167.94

Own +0%
Grant·A
May 14, 26

Lauren Mastrocola

Principal Accounting Officer

$21.3K

127 sh · $167.94

Own +1%
Grant·A
May 14, 26

Timothy Edwin Kelly KEY

Chief Financial Officer

$20.3K

121 sh · $167.94

Own +0%
Other·D
May 5, 26

Jeffrey B Kindler

Director

—

1.7K sh

Own -100%
Other·D
May 5, 26

Jeffrey B Kindler

Director

—

22.0K sh

Own -100%
Other·D
May 5, 26

Jeffrey B Kindler

Director

—

28.5K sh

Own -100%
Other·D
May 5, 26

Jeffrey B Kindler

Director

—

4.7K sh

Own -100%
Other·D
May 5, 26

Jeffrey B Kindler

Director

—

10.7K sh

Own -100%
Other·D
May 5, 26

Jeffrey B Kindler

Director

—

45.0K sh

Own -100%
Other·D
May 5, 26

Jeffrey B Kindler

Director

—

32.0K sh

Own -100%
Exercise·M
Mar 13, 26

Jeffrey B Kindler

Director

$0

71.8K sh

Own New
Exercise·M
Mar 13, 26

Jeffrey B Kindler

Director

—

71.8K sh

Own +55%
Grant·A
Mar 10, 26

Jeffrey B Kindler

Director

$0

41.1K sh

Own New
Grant·A
Mar 10, 26

Jeffrey B Kindler

Director

$0

35.6K sh

Own New
Grant·A
Mar 10, 26

Jeffrey B Kindler

Director

$69.0K

19.7K sh · $3.51

Own +18%
Grant·A
Feb 6, 26

Jeffrey B Kindler

Director

$0

224 sh

Own New
Grant·A
Feb 6, 26

Jeffrey B Kindler

Director

$0

478 sh

Own +69%
Grant·A
Feb 6, 26

Jeffrey B Kindler

Director

$0

688 sh

Own New
Grant·A
Feb 6, 26

Stuart A Arbuckle

Director

$0

224 sh

Own New
Grant·A
Feb 6, 26

Stuart A Arbuckle

Director

$0

478 sh

Own +69%
Grant·A
Feb 6, 26

Stuart A Arbuckle

Director

$0

688 sh

Own New
Grant·A
Feb 1, 26

Jeffrey B Kindler

Director

$0

1.7K sh

Own New
Other·F
Jan 12, 26

Megan Sniecinski

Chief Operating Officer

$244.0K

885 sh · $275.74

Own -3%
Other·F
Jan 12, 26

Alex Nemiroff

General Counsel and Secretary

$211.8K

768 sh · $275.74

Own -3%
Other·F
Jan 12, 26

Lauren Mastrocola

Principal Accounting Officer

$94.9K

344 sh · $275.74

Own -2%
Other·F
Jan 12, 26

Timothy Edwin Kelly KEY

Chief Financial Officer

$260.0K

943 sh · $275.74

Own -3%
Other·F
Jan 10, 26

Megan Sniecinski

Chief Operating Officer

$313.5K

1.1K sh · $288.45

Own -4%
Other·F
Jan 10, 26

Marcio Souza KEY

Chief Executive Officer

$1.2M

4.3K sh · $288.45

Own -5%
Other·F
Jan 10, 26

Alex Nemiroff

General Counsel and Secretary

$264.5K

917 sh · $288.45

Own -3%
Other·F
Jan 10, 26

Lauren Mastrocola

Principal Accounting Officer

$105.9K

367 sh · $288.45

Own -3%
Other·F
Jan 10, 26

Timothy Edwin Kelly KEY

Chief Financial Officer

$385.1K

1.3K sh · $288.45

Own -4%
Grant·A
Jan 8, 26

Megan Sniecinski

Chief Operating Officer

$0

7.7K sh

Own New
Grant·A
Jan 8, 26

Megan Sniecinski

Chief Operating Officer

$0

9.6K sh

Own +46%
Grant·A
Jan 8, 26

Marcio Souza KEY

Chief Executive Officer

$0

22.1K sh

Own New
Grant·A
Jan 8, 26

Marcio Souza KEY

Chief Executive Officer

$0

27.6K sh

Own +52%
Grant·A
Jan 8, 26

Alex Nemiroff

General Counsel and Secretary

$0

5.5K sh

Own New
Grant·A
Jan 8, 26

Alex Nemiroff

General Counsel and Secretary

$0

6.9K sh

Own +33%
Grant·A
Jan 8, 26

Lauren Mastrocola

Principal Accounting Officer

$0

7.5K sh

Own New
Grant·A
Jan 8, 26

Lauren Mastrocola

Principal Accounting Officer

$0

3.8K sh

Own +36%
Grant·A
Jan 8, 26

Timothy Edwin Kelly KEY

Chief Financial Officer

$0

7.0K sh

Own New
Grant·A
Jan 8, 26

Timothy Edwin Kelly KEY

Chief Financial Officer

$0

8.8K sh

Own +36%
Other·F
Jan 7, 26

Marcio Souza KEY

Chief Executive Officer

$118.5K

405 sh · $292.63

Own -1%
Other·F
Jan 7, 26

Alex Nemiroff

General Counsel and Secretary

$26.0K

89 sh · $292.63

Own -0%
Other·F
Jan 7, 26

Lauren Mastrocola

Principal Accounting Officer

$10.2K

35 sh · $292.63

Own -0%
Other·F
Jan 7, 26

Timothy Edwin Kelly KEY

Chief Financial Officer

$40.7K

139 sh · $292.63

Own -1%

Date▾	Insider	Role	Type	Shares	Own Δ	Price	Value
Jun 12, 2026	Dean J Mitchell	Director	Grant A	13.4K	New	—	$0
Jun 12, 2026	Dean J Mitchell	Director	Grant A	6.0K	+7%	—	$0
Jun 10, 2026	William D Young	Director	Grant A	648	New	—	$0
Jun 10, 2026	William D Young	Director	Grant A	1.4K	+72%	—	$0
Jun 10, 2026	Dean J Mitchell	Director	Grant A	648	New	—	$0
Jun 10, 2026	Dean J Mitchell	Director	Grant A	1.4K	+8%	—	$0
Jun 10, 2026	Jeffrey B Kindler	Director	Grant A	648	New	—	$0
Jun 10, 2026	Jeffrey B Kindler	Director	Grant A	1.4K	+118%	—	$0
Jun 10, 2026	Jill Desimone	Director	Grant A	648	New	—	$0
Jun 10, 2026	Jill Desimone	Director	Grant A	1.4K	+142%	—	$0
Jun 10, 2026	Merit Ester Cudkowicz	Director	Grant A	648	New	—	$0
Jun 10, 2026	Merit Ester Cudkowicz	Director	Grant A	1.4K	New	—	$0
Jun 10, 2026	Jeffrey Chodakewitz	Director	Grant A	648	New	—	$0
Jun 10, 2026	Jeffrey Chodakewitz	Director	Grant A	1.4K	New	—	$0
Jun 10, 2026	Stuart A Arbuckle	Director	Grant A	648	New	—	$0
Jun 10, 2026	Stuart A Arbuckle	Director	Grant A	1.4K	+118%	—	$0
May 14, 2026	Megan Sniecinski	Chief Operating Officer	Grant A	89	+0%	$167.94	$14.9K
May 14, 2026	Marcio Souza KEY	Chief Executive Officer	Grant A	126	+0%	$167.94	$21.2K
May 14, 2026	Alex Nemiroff	General Counsel and Secretary	Grant A	78	+0%	$167.94	$13.1K
May 14, 2026	Lauren Mastrocola	Principal Accounting Officer	Grant A	127	+1%	$167.94	$21.3K
May 14, 2026	Timothy Edwin Kelly KEY	Chief Financial Officer	Grant A	121	+0%	$167.94	$20.3K
May 5, 2026	Jeffrey B Kindler	Director	Other D	1.7K	-100%	—	—
May 5, 2026	Jeffrey B Kindler	Director	Other D	22.0K	-100%	—	—
May 5, 2026	Jeffrey B Kindler	Director	Other D	28.5K	-100%	—	—
May 5, 2026	Jeffrey B Kindler	Director	Other D	4.7K	-100%	—	—
May 5, 2026	Jeffrey B Kindler	Director	Other D	10.7K	-100%	—	—
May 5, 2026	Jeffrey B Kindler	Director	Other D	45.0K	-100%	—	—
May 5, 2026	Jeffrey B Kindler	Director	Other D	32.0K	-100%	—	—
Mar 13, 2026	Jeffrey B Kindler	Director	Exercise M	71.8K	New	—	$0
Mar 13, 2026	Jeffrey B Kindler	Director	Exercise M	71.8K	+55%	—	—
Mar 10, 2026	Jeffrey B Kindler	Director	Grant A	41.1K	New	—	$0
Mar 10, 2026	Jeffrey B Kindler	Director	Grant A	35.6K	New	—	$0
Mar 10, 2026	Jeffrey B Kindler	Director	Grant A	19.7K	+18%	$3.51	$69.0K
Feb 6, 2026	Jeffrey B Kindler	Director	Grant A	224	New	—	$0
Feb 6, 2026	Jeffrey B Kindler	Director	Grant A	478	+69%	—	$0
Feb 6, 2026	Jeffrey B Kindler	Director	Grant A	688	New	—	$0
Feb 6, 2026	Stuart A Arbuckle	Director	Grant A	224	New	—	$0
Feb 6, 2026	Stuart A Arbuckle	Director	Grant A	478	+69%	—	$0
Feb 6, 2026	Stuart A Arbuckle	Director	Grant A	688	New	—	$0
Feb 1, 2026	Jeffrey B Kindler	Director	Grant A	1.7K	New	—	$0
Jan 12, 2026	Megan Sniecinski	Chief Operating Officer	Other F	885	-3%	$275.74	$244.0K
Jan 12, 2026	Alex Nemiroff	General Counsel and Secretary	Other F	768	-3%	$275.74	$211.8K
Jan 12, 2026	Lauren Mastrocola	Principal Accounting Officer	Other F	344	-2%	$275.74	$94.9K
Jan 12, 2026	Timothy Edwin Kelly KEY	Chief Financial Officer	Other F	943	-3%	$275.74	$260.0K
Jan 10, 2026	Megan Sniecinski	Chief Operating Officer	Other F	1.1K	-4%	$288.45	$313.5K
Jan 10, 2026	Marcio Souza KEY	Chief Executive Officer	Other F	4.3K	-5%	$288.45	$1.2M
Jan 10, 2026	Alex Nemiroff	General Counsel and Secretary	Other F	917	-3%	$288.45	$264.5K
Jan 10, 2026	Lauren Mastrocola	Principal Accounting Officer	Other F	367	-3%	$288.45	$105.9K
Jan 10, 2026	Timothy Edwin Kelly KEY	Chief Financial Officer	Other F	1.3K	-4%	$288.45	$385.1K
Jan 8, 2026	Megan Sniecinski	Chief Operating Officer	Grant A	7.7K	New	—	$0
Jan 8, 2026	Megan Sniecinski	Chief Operating Officer	Grant A	9.6K	+46%	—	$0
Jan 8, 2026	Marcio Souza KEY	Chief Executive Officer	Grant A	22.1K	New	—	$0
Jan 8, 2026	Marcio Souza KEY	Chief Executive Officer	Grant A	27.6K	+52%	—	$0
Jan 8, 2026	Alex Nemiroff	General Counsel and Secretary	Grant A	5.5K	New	—	$0
Jan 8, 2026	Alex Nemiroff	General Counsel and Secretary	Grant A	6.9K	+33%	—	$0
Jan 8, 2026	Lauren Mastrocola	Principal Accounting Officer	Grant A	7.5K	New	—	$0
Jan 8, 2026	Lauren Mastrocola	Principal Accounting Officer	Grant A	3.8K	+36%	—	$0
Jan 8, 2026	Timothy Edwin Kelly KEY	Chief Financial Officer	Grant A	7.0K	New	—	$0
Jan 8, 2026	Timothy Edwin Kelly KEY	Chief Financial Officer	Grant A	8.8K	+36%	—	$0
Jan 7, 2026	Marcio Souza KEY	Chief Executive Officer	Other F	405	-1%	$292.63	$118.5K
Jan 7, 2026	Alex Nemiroff	General Counsel and Secretary	Other F	89	-0%	$292.63	$26.0K
Jan 7, 2026	Lauren Mastrocola	Principal Accounting Officer	Other F	35	-0%	$292.63	$10.2K
Jan 7, 2026	Timothy Edwin Kelly KEY	Chief Financial Officer	Other F	139	-1%	$292.63	$40.7K

About PRAX insider trading

This page tracks insider transactions for Praxis Precision Medicines, Inc. (PRAX) reported to the U.S. Securities and Exchange Commission on Form 4. Corporate insiders — directors, executive officers and beneficial owners of more than 10% of the stock — must disclose their trades within two business days. Open-market purchases (code P) and sales (code S) made at the insider's discretion are the most-watched opportunistic signals, while awards (A), option exercises (M) and tax-withholding (F) reflect compensation rather than conviction. Trades marked 10b5-1 were made under a pre-arranged plan and are considered routine. A cluster buy — several insiders buying within a short window — is historically a stronger bullish indicator than any single trade.