BAKER BROS. ADVISORS LP

Insider

Director, 10% Owner

Trades at: MDGL· ONC· PRLD· INCY· DNLI· ACAD· KNSA· TCRX +8 more

30D 90D 1Y

Net shares · 90d

+2.2M

2.3M buy · 11.0K sell

Net value · 90d

$9.7M

$10.0M in · $262.0K out

Sentiment · 90d

Net buying

97% buying · 3% selling

Open-market trades · 90d

2.3M buy · 11.0K sell

Trading track record · all companies

Running net of open-market buys − sells across every company. Tap the line or a marker for details. ▲ buy · ▼ sell.

Transactions · 90d

Open-market Buys Sells All types

MDGL Grant·A
Jun 17, 26

Director

$0

3.1K sh · 2 lots

Own New
MDGL Grant·A
Jun 17, 26

Director

$0

1.8K sh · 2 lots

Own +0%
ONC Grant·A
Jun 11, 26

Director

$0

38.0K sh · 2 lots

Own +31%
PRLD Grant·A
Jun 9, 26

Director, 10% Owner

$0

76.0K sh · 2 lots

Own New
INCY Grant·A
Jun 8, 26

Director, 10% Owner

$0

12.2K sh · 2 lots

Own New
INCY Grant·A
Jun 8, 26

Director, 10% Owner

$0

3.3K sh · 2 lots

Own +0%
DNLI Grant·A
Jun 3, 26

Director

$0

38.5K sh · 2 lots

Own New
DNLI Grant·A
Jun 3, 26

Director

$0

12.8K sh · 2 lots

Own +0%
ACAD Grant·A
May 29, 26

Director, 10% Owner

$0

64.0K sh · 2 lots

Own New
ACAD Grant·A
May 29, 26

Director, 10% Owner

$0

37.2K sh · 2 lots

Own +0%
KNSA Grant·A
May 29, 26

Director

$0

72.9K sh · 2 lots

Own New
KNSA Grant·A
May 29, 26

Director

$0

12.2K sh · 2 lots

Own +0%
ONC Sell·S
May 22, 26

Director

$262.0K

11.0K sh · $23.82 avg · 4 lots

Own -7%
TCRX Grant·A
May 20, 26

Director

$0

134.0K sh · 2 lots

Own New
INCY Exercise·M
May 8, 26

Director, 10% Owner

$0

30.0K sh · 2 lots

Own New
INCY Exercise·M
May 8, 26

Director, 10% Owner

$2.5M

30.0K sh · $84.53 avg · 2 lots

Own +0%
PRLD Buy·P
Apr 21, 26

Director, 10% Owner

$10.0M

2.3M sh · $4.44 avg · 2 lots

Own +13%
REPL Grant·A
Apr 1, 26

Director, 10% Owner

$0

89.0K sh · 2 lots

Own New
INCY Grant·A
Mar 31, 26

Director, 10% Owner

$0

842 sh · 2 lots

Own +0%

Date▾	Ticker	Role	Type	Shares	Own Δ	Price	Value
Jun 17, 2026	MDGL	Director	Grant A	3.1K2 lots	New	—	$0
Jun 17, 2026	MDGL	Director	Grant A	1.8K2 lots	+0%	—	$0
Jun 11, 2026	ONC	Director	Grant A	38.0K2 lots	+31%	—	$0
Jun 9, 2026	PRLD	Director, 10% Owner	Grant A	76.0K2 lots	New	—	$0
Jun 8, 2026	INCY	Director, 10% Owner	Grant A	12.2K2 lots	New	—	$0
Jun 8, 2026	INCY	Director, 10% Owner	Grant A	3.3K2 lots	+0%	—	$0
Jun 3, 2026	DNLI	Director	Grant A	38.5K2 lots	New	—	$0
Jun 3, 2026	DNLI	Director	Grant A	12.8K2 lots	+0%	—	$0
May 29, 2026	ACAD	Director, 10% Owner	Grant A	64.0K2 lots	New	—	$0
May 29, 2026	ACAD	Director, 10% Owner	Grant A	37.2K2 lots	+0%	—	$0
May 29, 2026	KNSA	Director	Grant A	72.9K2 lots	New	—	$0
May 29, 2026	KNSA	Director	Grant A	12.2K2 lots	+0%	—	$0
May 22, 2026	ONC	Director	Sell S	11.0K4 lots	-7%	$23.82 avg	$262.0K
May 20, 2026	TCRX	Director	Grant A	134.0K2 lots	New	—	$0
May 8, 2026	INCY	Director, 10% Owner	Exercise M	30.0K2 lots	New	—	$0
May 8, 2026	INCY	Director, 10% Owner	Exercise M	30.0K2 lots	+0%	$84.53 avg	$2.5M
Apr 21, 2026	PRLD	Director, 10% Owner	Buy P	2.3M2 lots	+13%	$4.44 avg	$10.0M
Apr 1, 2026	REPL	Director, 10% Owner	Grant A	89.0K2 lots	New	—	$0
Mar 31, 2026	INCY	Director, 10% Owner	Grant A	8422 lots	+0%	—	$0

Buy Sell Non-market (grant · exercise · gift)

About BAKER BROS. ADVISORS LP

This profile aggregates every SEC Form 4 insider transaction reported by BAKER BROS. ADVISORS LP across all companies they trade. Open-market purchases (code P) and sales (code S) are the highest-signal, discretionary trades; grants (A), option exercises (M) and gifts (G) reflect compensation rather than conviction and carry no market price. Figures cover the selected period and update as new filings are ingested.