FMR LLC

Insider

Other, 10% Owner

Trades at: AVLN· GPCR· MTSR· BEAM· SANA· BCAX· NMRA· TSBX +7 more

30D 90D 1Y

Net shares · 90d

-17.5K

0 buy · 17.5K sell

Net value · 90d

-$961.1K

$0 in · $961.1K out

Sentiment · 90d

Net selling

0% buying · 100% selling

Open-market trades · 90d

0 buy · 17.5K sell

Net buy / sell volume (all companies)

Tap or hover the chart for daily net volume. Green = net buying, red = net selling.

All transactions

Show open-market only

AVLN Exercise·C
May 1, 26

Other, 10% Owner

—

377.9K sh

Own New
AVLN Exercise·C
May 1, 26

Other, 10% Owner

—

225.8K sh

Own New
AVLN Exercise·C
May 1, 26

Other, 10% Owner

—

872.9K sh

Own New
AVLN Exercise·C
May 1, 26

Other, 10% Owner

—

80.3K sh

Own New
AVLN Exercise·C
May 1, 26

Other, 10% Owner

—

727.6K sh

Own New
AVLN Exercise·C
May 1, 26

Other, 10% Owner

—

377.9K sh

Own +20%
AVLN Exercise·C
May 1, 26

Other, 10% Owner

—

225.8K sh

Own +13%
AVLN Exercise·C
May 1, 26

Other, 10% Owner

—

872.9K sh

Own +108%
AVLN Exercise·C
May 1, 26

Other, 10% Owner

—

80.3K sh

Own +11%
AVLN Exercise·C
May 1, 26

Other, 10% Owner

—

727.6K sh

Own New
GPCR Sell·S
Apr 14, 26

Other, 10% Owner

$885.8K

16.1K sh · $55.07

Own -33%
GPCR Sell·S
Apr 14, 26

Other, 10% Owner

$75.3K

1.4K sh · $55.07

Own -33%

Date▾	Ticker	Role	Type	Shares	Own Δ	Price	Value
May 1, 2026	AVLN	Other, 10% Owner	Exercise C	377.9K	New	—	—
May 1, 2026	AVLN	Other, 10% Owner	Exercise C	225.8K	New	—	—
May 1, 2026	AVLN	Other, 10% Owner	Exercise C	872.9K	New	—	—
May 1, 2026	AVLN	Other, 10% Owner	Exercise C	80.3K	New	—	—
May 1, 2026	AVLN	Other, 10% Owner	Exercise C	727.6K	New	—	—
May 1, 2026	AVLN	Other, 10% Owner	Exercise C	377.9K	+20%	—	—
May 1, 2026	AVLN	Other, 10% Owner	Exercise C	225.8K	+13%	—	—
May 1, 2026	AVLN	Other, 10% Owner	Exercise C	872.9K	+108%	—	—
May 1, 2026	AVLN	Other, 10% Owner	Exercise C	80.3K	+11%	—	—
May 1, 2026	AVLN	Other, 10% Owner	Exercise C	727.6K	New	—	—
Apr 14, 2026	GPCR	Other, 10% Owner	Sell S	16.1K	-33%	$55.07	$885.8K
Apr 14, 2026	GPCR	Other, 10% Owner	Sell S	1.4K	-33%	$55.07	$75.3K

About FMR LLC

This profile aggregates every SEC Form 4 insider transaction reported by FMR LLC across all companies they trade. Open-market purchases (code P) and sales (code S) are the highest-signal, discretionary trades; grants (A), option exercises (M) and gifts (G) reflect compensation rather than conviction and carry no market price. Figures cover the selected period and update as new filings are ingested.