LOSCALZO JOSEPH

Insider

Director

Trades at: IONS· LPTX

30D 90D 1Y

Net shares · 365d

-110.3K

0 buy · 110.3K sell

Net value · 365d

-$8.0M

$0 in · $8.0M out

Sentiment · 365d

Net selling

0% buying · 100% selling

Open-market trades · 365d

0 buy · 110.3K sell

Trading track record · all companies

Running net of open-market buys − sells across every company. Tap the line or a marker for details. ▲ buy · ▼ sell.

Transactions · 365d

Open-market Buys Sells All types

IONS Exercise·M
May 4, 26

Director · 10b5-1

$0

77.3K sh · 6 lots

Own New
IONS Sell·S
May 4, 26

Director · 10b5-1

$5.8M

77.3K sh · $75.06 avg · 2 lots

Own -68%
IONS Exercise·M
May 4, 26

Director · 10b5-1

$3.8M

77.3K sh · $48.74 avg · 6 lots

Own +213%
LPTX Exercise·M
Mar 13, 26

Director

$0

168.8K sh · 2 lots

Own New
LPTX Exercise·M
Mar 13, 26

Director

—

168.8K sh · 2 lots

Own New
IONS Exercise·M
Mar 4, 26

Director · 10b5-1

$0

1.0K sh · 2 lots

Own +10%
IONS Sell·S
Mar 4, 26

Director · 10b5-1

$82.8K

1.0K sh · $80.27 avg · 2 lots

Own -3%
IONS Exercise·M
Mar 4, 26

Director · 10b5-1

$39.3K

1.0K sh · $38.06 avg · 2 lots

Own +3%
LPTX Grant·A
Dec 23, 25

Director

$0

94.0K sh

Own New
LPTX Grant·A
Nov 11, 25

Director

$0

74.7K sh

Own New
IONS Exercise·M
Oct 31, 25

Director · 10b5-1

$0

16.0K sh

Own New
IONS Exercise·M
Oct 31, 25

Director · 10b5-1

$835.5K

16.0K sh · $52.22

Own +44%
IONS Sell·S
Oct 31, 25

Director · 10b5-1

$1.2M

16.0K sh · $75.10

Own -31%
IONS Exercise·M
Sep 3, 25

Director

$0

16.0K sh

Own New
IONS Exercise·M
Sep 3, 25

Director

$390.7K

16.0K sh · $24.42

Own +44%
IONS Sell·S
Sep 3, 25

Director

$962.4K

16.0K sh · $60.15

Own -31%
IONS Exercise·M
Jul 15, 25

Director

$0

4.1K sh

Own +357%
IONS Exercise·M
Jul 15, 25

Director

$0

4.1K sh

Own +13%
IONS Grant·A
Jul 1, 25

Director

$0

16.7K sh · 2 lots

Own New

Date▾	Ticker	Role	Type	Shares	Own Δ	Price	Value
May 4, 2026	IONS	Director	Exercise M	77.3K6 lots	New	—	$0
May 4, 2026	IONS	Director	Sell S	77.3K2 lots	-68%	$75.06 avg	$5.8M
May 4, 2026	IONS	Director	Exercise M	77.3K6 lots	+213%	$48.74 avg	$3.8M
Mar 13, 2026	LPTX	Director	Exercise M	168.8K2 lots	New	—	$0
Mar 13, 2026	LPTX	Director	Exercise M	168.8K2 lots	New	—	—
Mar 4, 2026	IONS	Director	Exercise M	1.0K2 lots	+10%	—	$0
Mar 4, 2026	IONS	Director	Sell S	1.0K2 lots	-3%	$80.27 avg	$82.8K
Mar 4, 2026	IONS	Director	Exercise M	1.0K2 lots	+3%	$38.06 avg	$39.3K
Dec 23, 2025	LPTX	Director	Grant A	94.0K	New	—	$0
Nov 11, 2025	LPTX	Director	Grant A	74.7K	New	—	$0
Oct 31, 2025	IONS	Director	Exercise M	16.0K	New	—	$0
Oct 31, 2025	IONS	Director	Exercise M	16.0K	+44%	$52.22	$835.5K
Oct 31, 2025	IONS	Director	Sell S	16.0K	-31%	$75.10	$1.2M
Sep 3, 2025	IONS	Director	Exercise M	16.0K	New	—	$0
Sep 3, 2025	IONS	Director	Exercise M	16.0K	+44%	$24.42	$390.7K
Sep 3, 2025	IONS	Director	Sell S	16.0K	-31%	$60.15	$962.4K
Jul 15, 2025	IONS	Director	Exercise M	4.1K	+357%	—	$0
Jul 15, 2025	IONS	Director	Exercise M	4.1K	+13%	—	$0
Jul 1, 2025	IONS	Director	Grant A	16.7K2 lots	New	—	$0

Buy Sell Non-market (grant · exercise · gift)

About LOSCALZO JOSEPH

This profile aggregates every SEC Form 4 insider transaction reported by LOSCALZO JOSEPH across all companies they trade. Open-market purchases (code P) and sales (code S) are the highest-signal, discretionary trades; grants (A), option exercises (M) and gifts (G) reflect compensation rather than conviction and carry no market price. Figures cover the selected period and update as new filings are ingested.