Opaleye Management Inc.

Insider

10% Owner

Trades at: ACOG· SLGL· SNWV· HROW· CDXS· ETON· TARA· TCON +1 more

30D 90D 1Y

Net shares · 90d

+90.7K

213.4K buy · 122.7K sell

Net value · 90d

-$649.4K

$1.5M in · $2.2M out

Sentiment · 90d

Net buying

41% buying · 59% selling

Open-market trades · 90d

213.4K buy · 122.7K sell

Net buy / sell volume (all companies)

Tap or hover the chart for daily net volume. Green = net buying, red = net selling.

All transactions · open-market

Include grants & non-market

ACOG Buy·P
Jun 15, 26

10% Owner

$27.3K

4.5K sh · $5.99

Own +0%
ACOG Buy·P
Jun 12, 26

10% Owner

$1.6K

273 sh · $5.93

Own +0%
ACOG Buy·P
Jun 11, 26

10% Owner

$16.9K

2.9K sh · $5.91

Own +0%
ACOG Buy·P
Jun 10, 26

10% Owner

$35.2K

5.9K sh · $5.99

Own +0%
ACOG Buy·P
Jun 9, 26

10% Owner

$148.5K

24.9K sh · $5.98

Own +1%
ACOG Buy·P
Jun 5, 26

10% Owner

$58.6K

10.1K sh · $5.83

Own +0%
ACOG Buy·P
May 29, 26

10% Owner

$416.4K

70.6K sh · $5.90

Own +3%
ACOG Buy·P
May 28, 26

10% Owner

$11.7K

2.0K sh · $5.83

Own +0%
ACOG Buy·P
May 27, 26

10% Owner

$6.7K

1.2K sh · $5.73

Own +0%
ACOG Buy·P
May 21, 26

10% Owner

$90.9K

15.9K sh · $5.70

Own +1%
SLGL Buy·P
May 20, 26

10% Owner

$100.7K

1.6K sh · $64.43

Own +0%
ACOG Buy·P
May 20, 26

10% Owner

$49.7K

8.4K sh · $5.89

Own +0%
ACOG Buy·P
May 18, 26

10% Owner

$99.0K

17.4K sh · $5.69

Own +1%
ACOG Buy·P
May 15, 26

10% Owner

$97.0K

16.6K sh · $5.83

Own +1%
SLGL Buy·P
May 13, 26

10% Owner

$129.5K

1.9K sh · $66.87

Own +0%
SLGL Buy·P
May 12, 26

10% Owner

$102.0K

1.5K sh · $67.98

Own +0%
SNWV Sell·S
May 1, 26

10% Owner

$8.1K

500 sh · $16.11

Own -9%
SNWV Sell·S
May 1, 26

10% Owner

$162.4K

10.1K sh · $16.11

Own -1%
SNWV Sell·S
Apr 30, 26

10% Owner

$16.2K

1.0K sh · $16.15

Own -15%
SNWV Sell·S
Apr 30, 26

10% Owner

$387.6K

24.0K sh · $16.15

Own -3%
SNWV Sell·S
Apr 29, 26

10% Owner

$17.2K

1.0K sh · $17.25

Own -13%
SNWV Sell·S
Apr 29, 26

10% Owner

$402.9K

23.4K sh · $17.25

Own -3%
SNWV Sell·S
Apr 28, 26

10% Owner

$46.2K

2.5K sh · $18.47

Own -25%
SNWV Sell·S
Apr 28, 26

10% Owner

$808.7K

43.8K sh · $18.47

Own -5%
SNWV Sell·S
Apr 21, 26

10% Owner

$4.1K

202 sh · $20.50

Own -0%
SNWV Sell·S
Apr 17, 26

10% Owner

$102.3K

5.0K sh · $20.46

Own -33%
SNWV Sell·S
Apr 17, 26

10% Owner

$230.5K

11.3K sh · $20.46

Own -1%
ACOG Buy·P
Mar 30, 26

TenPercentOwner

$9.2K

1.9K sh · $4.99

Own +0%
ACOG Buy·P
Mar 27, 26

TenPercentOwner

$50.8K

10.0K sh · $5.08

Own +0%
ACOG Buy·P
Mar 26, 26

TenPercentOwner

$38.6K

7.3K sh · $5.28

Own +0%
ACOG Buy·P
Mar 25, 26

TenPercentOwner

$46.6K

8.6K sh · $5.43

Own +0%

Date▾	Ticker	Role	Type	Shares	Own Δ	Price	Value
Jun 15, 2026	ACOG	10% Owner	Buy P	4.5K	+0%	$5.99	$27.3K
Jun 12, 2026	ACOG	10% Owner	Buy P	273	+0%	$5.93	$1.6K
Jun 11, 2026	ACOG	10% Owner	Buy P	2.9K	+0%	$5.91	$16.9K
Jun 10, 2026	ACOG	10% Owner	Buy P	5.9K	+0%	$5.99	$35.2K
Jun 9, 2026	ACOG	10% Owner	Buy P	24.9K	+1%	$5.98	$148.5K
Jun 5, 2026	ACOG	10% Owner	Buy P	10.1K	+0%	$5.83	$58.6K
May 29, 2026	ACOG	10% Owner	Buy P	70.6K	+3%	$5.90	$416.4K
May 28, 2026	ACOG	10% Owner	Buy P	2.0K	+0%	$5.83	$11.7K
May 27, 2026	ACOG	10% Owner	Buy P	1.2K	+0%	$5.73	$6.7K
May 21, 2026	ACOG	10% Owner	Buy P	15.9K	+1%	$5.70	$90.9K
May 20, 2026	SLGL	10% Owner	Buy P	1.6K	+0%	$64.43	$100.7K
May 20, 2026	ACOG	10% Owner	Buy P	8.4K	+0%	$5.89	$49.7K
May 18, 2026	ACOG	10% Owner	Buy P	17.4K	+1%	$5.69	$99.0K
May 15, 2026	ACOG	10% Owner	Buy P	16.6K	+1%	$5.83	$97.0K
May 13, 2026	SLGL	10% Owner	Buy P	1.9K	+0%	$66.87	$129.5K
May 12, 2026	SLGL	10% Owner	Buy P	1.5K	+0%	$67.98	$102.0K
May 1, 2026	SNWV	10% Owner	Sell S	500	-9%	$16.11	$8.1K
May 1, 2026	SNWV	10% Owner	Sell S	10.1K	-1%	$16.11	$162.4K
Apr 30, 2026	SNWV	10% Owner	Sell S	1.0K	-15%	$16.15	$16.2K
Apr 30, 2026	SNWV	10% Owner	Sell S	24.0K	-3%	$16.15	$387.6K
Apr 29, 2026	SNWV	10% Owner	Sell S	1.0K	-13%	$17.25	$17.2K
Apr 29, 2026	SNWV	10% Owner	Sell S	23.4K	-3%	$17.25	$402.9K
Apr 28, 2026	SNWV	10% Owner	Sell S	2.5K	-25%	$18.47	$46.2K
Apr 28, 2026	SNWV	10% Owner	Sell S	43.8K	-5%	$18.47	$808.7K
Apr 21, 2026	SNWV	10% Owner	Sell S	202	-0%	$20.50	$4.1K
Apr 17, 2026	SNWV	10% Owner	Sell S	5.0K	-33%	$20.46	$102.3K
Apr 17, 2026	SNWV	10% Owner	Sell S	11.3K	-1%	$20.46	$230.5K
Mar 30, 2026	ACOG	TenPercentOwner	Buy P	1.9K	+0%	$4.99	$9.2K
Mar 27, 2026	ACOG	TenPercentOwner	Buy P	10.0K	+0%	$5.08	$50.8K
Mar 26, 2026	ACOG	TenPercentOwner	Buy P	7.3K	+0%	$5.28	$38.6K
Mar 25, 2026	ACOG	TenPercentOwner	Buy P	8.6K	+0%	$5.43	$46.6K

About Opaleye Management Inc.

This profile aggregates every SEC Form 4 insider transaction reported by Opaleye Management Inc. across all companies they trade. Open-market purchases (code P) and sales (code S) are the highest-signal, discretionary trades; grants (A), option exercises (M) and gifts (G) reflect compensation rather than conviction and carry no market price. Figures cover the selected period and update as new filings are ingested.